KIDINS220 Antikörper (pSer918)
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- Target Alle KIDINS220 Antikörper anzeigen
- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
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Bindungsspezifität
- pSer918
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KIDINS220 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Cow,Pig,Chicken,Rabbit,Guinea Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Kidins220 around the phosphorylation site of Ser918
- Isotyp
- IgG
- Top Product
- Discover our top product KIDINS220 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
- Andere Bezeichnung
- Kidins220 (KIDINS220 Produkte)
- Synonyme
- ARMS antikoerper, fj35h03 antikoerper, kidins220 antikoerper, zgc:63531 antikoerper, dZ119J18.2 antikoerper, wu:fj35h03 antikoerper, 3110039L19Rik antikoerper, AI194387 antikoerper, AI316525 antikoerper, C330002I19Rik antikoerper, mKIAA1250 antikoerper, kinase D interacting substrate 220 antikoerper, kinase D-interacting substrate 220 antikoerper, kinase D-interacting substrate 220b antikoerper, kinase D-interacting substrate 220kDa antikoerper, KIDINS220 antikoerper, Kidins220 antikoerper, kidins220b antikoerper
- Hintergrund
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Synonyms: Kidins220 phospho S918, Ankyrin repeat-rich membrane-spanning protein, arms, KDIS_HUMAN, Kidins220, Kinase D interacting substance of 220 kDa, Kinase D-interacting substrate of 220 kDa, rgd 619949.
Background: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.
- Gen-ID
- 57498
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