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KIDINS220 Antikörper (pSer918)

KIDINS220 Reaktivität: Ratte WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN722095
  • Target Alle KIDINS220 Antikörper anzeigen
    KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
    Bindungsspezifität
    • 11
    • 9
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer918
    Reaktivität
    • 39
    • 13
    • 11
    • 1
    Ratte
    Wirt
    • 39
    • 10
    Kaninchen
    Klonalität
    • 39
    • 10
    Polyklonal
    Konjugat
    • 22
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser KIDINS220 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 17
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Cow,Pig,Chicken,Rabbit,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Kidins220 around the phosphorylation site of Ser918
    Isotyp
    IgG
    Top Product
    Discover our top product KIDINS220 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
    Andere Bezeichnung
    Kidins220 (KIDINS220 Produkte)
    Synonyme
    ARMS antikoerper, fj35h03 antikoerper, kidins220 antikoerper, zgc:63531 antikoerper, dZ119J18.2 antikoerper, wu:fj35h03 antikoerper, 3110039L19Rik antikoerper, AI194387 antikoerper, AI316525 antikoerper, C330002I19Rik antikoerper, mKIAA1250 antikoerper, kinase D interacting substrate 220 antikoerper, kinase D-interacting substrate 220 antikoerper, kinase D-interacting substrate 220b antikoerper, kinase D-interacting substrate 220kDa antikoerper, KIDINS220 antikoerper, Kidins220 antikoerper, kidins220b antikoerper
    Hintergrund

    Synonyms: Kidins220 phospho S918, Ankyrin repeat-rich membrane-spanning protein, arms, KDIS_HUMAN, Kidins220, Kinase D interacting substance of 220 kDa, Kinase D-interacting substrate of 220 kDa, rgd 619949.

    Background: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.

    Gen-ID
    57498
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