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Rekombinanter SIRPG Antikörper

SIRPG Reaktivität: Human ELISA, FACS, IP, BR Wirt: Maus Monoclonal OX-119 unconjugated Recombinant Antibody
Produktnummer ABIN7543054
  • Target Alle SIRPG Antikörper anzeigen
    SIRPG (Signal-Regulatory Protein gamma (SIRPG))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 46
    • 7
    • 7
    • 3
    • 3
    • 1
    Human
    Wirt
    • 30
    • 16
    Maus
    Klonalität
    • 30
    • 15
    • 1
    Monoklonal
    Konjugat
    • 25
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SIRPG Antikörper ist unkonjugiert
    Applikation
    • 25
    • 18
    • 15
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)
    Verwendungszweck
    Anti-SIRP g [OX-119], Mouse IgG1, kappa
    Spezifität
    Hybridoma supernatants were initially screened by ELISA, using SIRPg-CD4, human SIRPa-Fc, human SIRPb-Fc or CD4 to eliminate hybridomas with cross-reactivity to rat CD4, human SIRPa, and SIRPb. There is some marginal binding of OX-119 to SIRPb transfected 293T cells. SIRPg binds CD47. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells..
    Produktmerkmale

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    Aufreinigung
    Protein A affinity purified
    Immunogen
    OX-119 was prepared by immunizing BALB/c mice with a chimeric protein made up of human SIRPg and a leader peptide of rat CD4 domain (SIRPg-CD4 ).
    Klon
    OX-119
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product SIRPG Primärantikörper
  • Applikationshinweise
    OX-119 is able to perform staining of peripheral blood myeloid cells (PBMCs) and block SIRPg-mediated apoptosis. OX-119 can also be used in IP, FC and ELISA.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % Proclin 300.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    SIRPG (Signal-Regulatory Protein gamma (SIRPG))
    Andere Bezeichnung
    SIRP g (SIRPG Produkte)
    Hintergrund
    CD172g, OX119, MRC OX-119, MRC OX119, SIRP-g, SIRPg, SIRP gamma, SIRP-gamma, CD172 antigen-like family member B, signal-regulatory protein beta, CD172-g
    UniProt
    Q9P1W8
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