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TNF alpha Antikörper (AA 86-150) (HRP)

TNF alpha Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal HRP

Produktnummer ABIN724589

Datenblatt (PDF)

Target Alle TNF alpha Antikörper anzeigen

TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
Bindungsspezifität
43

32

15

15

13

10

8

6

5

5

5

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 86-150
Reaktivität
338

208

126

64

50

43

34

26

21

19

11

10

9

9

7

5

5

2

2

2

2

1

1

1

1
Human, Maus, Ratte, Schwein, Kaninchen
Wirt
267

204

46

25

6

4

4

2

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
281

273
Polyklonal
Konjugat
267

81

44

19

18

12

6

6

6

6

6

6

6

6

6

5

4

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1
Dieser TNF alpha Antikörper ist konjugiert mit HRP
Applikation
350

210

140

130

74

60

55

54

47

42

42

39

37

32

20

12

11

9

9

6

6

6

5

5

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human, Maus, Schwein, Kaninchen, Ratte

Homologie

Dog,Horse

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human TNF alpha

Isotyp

IgG

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anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 181-235) antibody
TNF alpha Reaktivität: Human, Maus, Ratte, Kaninchen, Pferd WB, ELISA, IHC (p), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) antibody
TNF alpha Reaktivität: Human, Ratte IHC, FACS, IF, StM Wirt: Maus Monoclonal TNFA-1172 unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 1-233) antibody
TNF alpha Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) antibody
TNF alpha Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) antibody (FITC)
TNF alpha Reaktivität: Human, Schwein, Non-Human Primate FACS Wirt: Maus Monoclonal MAb11 FITC

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 1-233) antibody
TNF alpha Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal M1-C4 unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 80-227) antibody
TNF alpha Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 80-235) antibody
TNF alpha Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 80-235) antibody
TNF alpha Reaktivität: Maus WB, IHC, IP, ICC Wirt: Maus Monoclonal C1 unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 71-234) antibody
TNF alpha Reaktivität: Rind (Kuh) WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit

12 months
Target

TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung

TNF alpha (TNF alpha Produkte)

Hintergrund

Synonyms: DIF, TNFA, TNFSF2, TNF-alpha, Tumor necrosis factor, Cachectin, Tumor necrosis factor ligand superfamily member 2, TNF-a, TNF
Background: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.

Molekulargewicht

17/26kDa

Gen-ID

7124

UniProt

P01375

Pathways

NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome