Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

APP Antikörper (AA 381-480)

Name: APP Antikörper (AA 381-480)
SKU: ABIN725120
Price: 384.62 EUR
Availability: InStock

APP Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Lane 1: A431 lysates Lane 2: Raji lysates Jurkat lysates probed with Amyloid Precursor Protein Antibody, Unconjugated at 1:300 dilution and 4˚C overnight incubation. (APP Antikörper (AA 381-480))

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-APP/Amyloid Precursor Protein Polyclonal Antibody (ABIN725120) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (APP Antikörper (AA 381-480))

IHC

Paraformaldehyde-fixed, paraffin embedded Rat Brain Antigen retrieval by boiling in sodium citrate buffer (pH6. (APP Antikörper (AA 381-480))

IHC (p)

Rat eye lysates probed with Amyloid Precursor Protein Antibody, Unconjugated at 1:300 dilution and 4˚C overnight incubation. (APP Antikörper (AA 381-480))

4 Abbildungen

(2 Referenzen)

Produktnummer ABIN725120

Datenblatt (PDF)

Target Alle APP Antikörper anzeigen

APP (Amyloid beta (A4) Precursor Protein (APP))
Bindungsspezifität
29

27

24

20

17

15

11

8

8

8

7

6

6

5

4

4

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 381-480
Reaktivität
229

109

105

12

10

10

9

9

9

8

7

5

4

3

2

1

1

1

1

1
Human, Maus, Ratte
Wirt
194

73

4

4

1
Kaninchen
Passende Sekundärantikörper
Klonalität
212

64
Polyklonal
Konjugat
142

24

19

18

7

6

4

4

4

4

4

4

4

4

4

4

4

2

2

2

2

2

2

2

2

1
Dieser APP Antikörper ist unkonjugiert
Applikation
177

127

75

51

51

43

39

29

27

15

14

6

3

2

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human, Maus, Ratte

Homologie

Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human of human APP

Isotyp

IgG

Top Product

Discover our top product APP Primärantikörper
anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibody
APP Reaktivität: Human WB, IF, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (AA 190-290) antibody
APP Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (AA 666-670) antibody
APP Reaktivität: Human, Maus, Ratte WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (AA 18-270) antibody
APP Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibody
APP Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) antibody
KO Validated APP Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Monoclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (pThr668) antibody
APP Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibody
APP Reaktivität: Human, Maus, Ratte WB, IHC (p), FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) (AA 18-286) antibody
APP Reaktivität: Maus WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Amyloid beta (A4) Precursor Protein (APP) antibody
APP Reaktivität: Human WB, ELISA, IHC, IF Wirt: Maus Monoclonal 5A11E5 unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Potter, Potter: "Molecular Anatomy of Palate Development." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132662, (2015) (PubMed).

Wang, Wang: "Studying the relationship between cell cycle and Alzheimer's disease by gold nanoparticle probes." in: Analytical biochemistry, Vol. 489, pp. 32-7, (2015) (PubMed).
Target

APP (Amyloid beta (A4) Precursor Protein (APP))

Andere Bezeichnung

Amyloid Precursor Protein (APP Produkte)

Hintergrund

Synonyms: AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, PN-II, CTFgamma, Amyloid beta A4 protein, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II, A4
Background: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Gen-ID

351

UniProt

P05067

Pathways

Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour