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tau Antikörper (AA 681-758)

Name: tau Antikörper (AA 681-758)
SKU: ABIN725600
Price: 384.62 EUR
Availability: InStock

Reaktivität: Human, Maus, Ratte WB, ELISA, IF (p), IF (cc), IHC (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-Tau protein Polyclonal Antibody (ABIN725600), Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (tau Antikörper (AA 681-758))

IHC

Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-Tau protein Polyclonal Antibody , Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (tau Antikörper (AA 681-758))

IHC (p)

Paraformaldehyde-fixed, paraffin embedded rat brain, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Tau protein Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C, followed by a conjugated secondary Goat Anti-Rabbit IgG, Cy3 conjugated-Cy3)used at 1:200 dilution for 40 minutes at 37°C. (tau Antikörper (AA 681-758))

IF (p)

3 Abbildungen

Produktnummer ABIN725600

Datenblatt (PDF)

Target Alle tau Antikörper anzeigen

tau (tau Protein)
Bindungsspezifität
31

31

30

30

27

27

25

25

24

24

24

23

23

22

17

17

17

16

16

16

16

16

15

15

13

12

11

10

9

8

7

7

6

5

5

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2
AA 681-758
Reaktivität
579

541

538

42

28

27

18

7

3

2

2

1

1
Human, Maus, Ratte
Wirt
684

38

3

2
Kaninchen
Passende Sekundärantikörper
Klonalität
661

65

1
Polyklonal
Konjugat
238

40

31

29

24

24

24

24

24

24

24

24

24

22

22

15

15

15

15

15

15

12

5

4

4

4

4

4

1

1
Dieser tau Antikörper ist unkonjugiert
Applikation
570

271

262

213

92

84

68

58

54

37

34

17

12

12

12

9

2

2

1

1
Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human, Maus, Ratte

Homologie

Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human Tau protein

Isotyp

IgG

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Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Target

tau (tau Protein)

Abstract

tau Produkte

Synonyme

DDPAC antikoerper, FTDP-17 antikoerper, MAPTL antikoerper, MSTD antikoerper, MTBT1 antikoerper, MTBT2 antikoerper, PPND antikoerper, TAU antikoerper, tau antikoerper, PHF-tau antikoerper, microtubule associated protein tau antikoerper, MAPT antikoerper

Hintergrund

Synonyms: TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, PPP1R103, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT
Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Gen-ID

4137

UniProt

P10636