HSPD1 Antikörper (AA 501-573)

Produktnummer ABIN726080

Produktdetails anti-HSPD1 Antikörper

Target: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Bindungsspezifität: AA 501-573

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Schwein, Ratte

Homologie: Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSP60

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-HSPD1 Antikörper (ABIN726080)

Liu, Cao, Li, Wang, Zhang, Dong Zhang, Liu, Yuan, Zhan: "Autophagy induced by DAMPs facilitates the inflammation response in lungs undergoing ischemia-reperfusion injury through promoting TRAF6 ubiquitination." in: Cell death and differentiation, Vol. 24, Issue 4, pp. 683-693, (2017) (PubMed).

Kengkoom, Ampawong: "Chronic ingestion of high dosed Phikud Navakot extraction induces mesangiolysis in rats with alteration of AQP1 and Hsp60 expressions." in: BioMed research international, Vol. 2015, pp. 462387, (2015) (PubMed).

Isarangkul, Wiyakrutta, Kengkoom, Reamtong, Ampawong: "Mitochondrial and cytoskeletal alterations are involved in the pathogenesis of hydronephrosis in ICR/Mlac-hydro mice." in: International journal of clinical and experimental medicine, Vol. 8, Issue 6, pp. 9192-204, (2015) (PubMed).

Qi, Chen, Chan, Li, Yuan, Yu, Lin, Yew, Kung, Lai: "Two-dimensional differential gel electrophoresis/analysis of diethylnitrosamine induced rat hepatocellular carcinoma." in: International journal of cancer, Vol. 122, Issue 12, pp. 2682-8, (2008) (PubMed).

Details zu HSPD1

Target: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Andere Bezeichnung: HSP60 (HSPD1 Produkte)

Hintergrund:

Synonyms: HLD4, CPN6, GROEL, HSP6, HSP65, SPG13, HSP-6, HuCHA6, 6 kDa heat shock protein, mitochondrial, 6 kDa chaperonin, Chaperonin 6, Heat shock protein 6, Mitochondrial matrix protein P1, P6 lymphocyte protein, HSPD1

Background: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

Gen-ID: 3329

UniProt: P10809

Pathways: Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity