PMP22 Antikörper (AA 101-160) (Biotin)
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- Target Alle PMP22 Antikörper anzeigen
- PMP22 (Peripheral Myelin Protein 22 (PMP22))
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Bindungsspezifität
- AA 101-160
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Reaktivität
- Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PMP22 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PMP-22
- Isotyp
- IgG
- Top Product
- Discover our top product PMP22 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- PMP22 (Peripheral Myelin Protein 22 (PMP22))
- Andere Bezeichnung
- PMP22 (PMP22 Produkte)
- Hintergrund
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Synonyms: DSS, HNPP, CMT1A, CMT1E, GAS-3, Sp110, HMSNIA, Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, PMP22, GAS3
Background: PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.
- Gen-ID
- 5376
- UniProt
- Q01453
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