VEGF Antikörper (AA 27-120)

Produktnummer ABIN727205

Der Kaninchen Polyklonal Anti-VEGF-Antikörper wurde für WB, ELISA, IHC (p), IHC (fro), IF (p) und FACS validiert. Er ist geeignet, VEGF in Proben von Human, Maus, Ratte, Schwein und Ziege zu detektieren. Es sind 14+ Publikationen verfügbar.

Kurzübersicht für VEGF Antikörper (AA 27-120) (ABIN727205)

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Reaktivität: Human, Maus, Ratte, Schwein, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VEGF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Produktdetails anti-VEGF Antikörper

Bindungsspezifität: AA 27-120

Kreuzreaktivität: Ziege, Human, Maus, Schwein, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VEGF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-VEGF Antikörper (ABIN727205)

Bi, Zhang, Du, Zhang, Deng, Liu, Zhang: "Peripheral serotonin regulates postoperative intra-abdominal adhesion formation in mice." in: Scientific reports, Vol. 7, Issue 1, pp. 10001, (2019) (PubMed).

Chen, Zhao, Li, Shou, Zheng, Li, Qi, Yu: "Circulating fibrocyte mobilization in negative pressure wound therapy." in: Journal of cellular and molecular medicine, Vol. 21, Issue 8, pp. 1513-1522, (2018) (PubMed).

Varghese, Joseph, S R, B S, Sreelekha: "The inhibitory effect of anti- tumor polysaccharide from Punica granatum on metastasis." in: International journal of biological macromolecules, Vol. 103, pp. 1000-1010, (2017) (PubMed).

Yasukawa, Fujihara, Fujimori, Kawaguchi, Yamada, Nakayama, Yamamoto, Kishi, Hamada, Masutani: "Synergetic Effects of PARP Inhibitor AZD2281 and Cisplatin in Oral Squamous Cell Carcinoma in Vitro and in Vivo." in: International journal of molecular sciences, Vol. 17, Issue 3, pp. 272, (2016) (PubMed).

Wang, Hao, Shi, Pu, Wang: "Effects of minocycline on apoptosis and angiogenesis-related protein expression in a rat model of intracerebral hemorrhage." in: Neural regeneration research, Vol. 7, Issue 8, pp. 595-600, (2015) (PubMed).

Li, Dong, Wei, Wang, Zhang, Li: "Fatty acid synthase mediates the epithelial-mesenchymal transition of breast cancer cells." in: International journal of biological sciences, Vol. 10, Issue 2, pp. 171-80, (2014) (PubMed).

Zhang, Li, Li, Chang, Chen, Jiang, Zhao, Guo: "Expression and localization of the vascular endothelial growth factor and changes of microvessel density during hair follicle development of Liaoning cashmere goats." in: Genetics and molecular research : GMR, Vol. 12, Issue 4, pp. 6424-32, (2014) (PubMed).

Zeng, Li, Dong, Ma, Jiang, Jin, Tu: "Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis." in: European journal of pharmacology, Vol. 714, Issue 1-3, pp. 261-73, (2013) (PubMed).

Ryzhov, Goldstein, Novitskiy, Blackburn, Biaggioni, Feoktistov: "Role of A2B adenosine receptors in regulation of paracrine functions of stem cell antigen 1-positive cardiac stromal cells." in: The Journal of pharmacology and experimental therapeutics, Vol. 341, Issue 3, pp. 764-74, (2012) (PubMed).

Qi, Qian, Sun, Liu, Wu, Sun: "Inhaled NO contributes to lung repair in piglets with acute respiratory distress syndrome via increasing circulating endothelial progenitor cells." in: PLoS ONE, Vol. 7, Issue 3, pp. e33859, (2012) (PubMed).

Guo, Chen, Huang, Li: "Combinatorial effects of naomai yihao capsules and vascular endothelial growth factor gene-transfected bone marrow mesenchymal stem cells on angiogenesis in cerebral ischemic tissues in rats." in: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, Vol. 32, Issue 1, pp. 87-92, (2012) (PubMed).

Details zu VEGF

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Andere Bezeichnung: VEGF

Hintergrund:

Synonyms: VPF, VEGF, MVCD1, Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VEGFA

Background: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Gen-ID: 7422

UniProt: P15692