Cyclin C Antikörper (AA 23-100) (Biotin)

Produktnummer ABIN727252

Produktdetails anti-Cyclin C Antikörper (Biotin)

Target: Cyclin C (CCNC)

Bindungsspezifität: AA 23-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin C Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cyclin C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Cyclin C

Target: Cyclin C (CCNC)

Andere Bezeichnung: Cyclin C (CCNC Produkte)

Synonyme: CG1C_DROME antikoerper, CG7281 antikoerper, CYCC antikoerper, Cln3 antikoerper, Cyc-C antikoerper, DmcycC antikoerper, Dmel\\CG7281 antikoerper, SRB11 antikoerper, cycC antikoerper, cyclinC antikoerper, dTRAP33 antikoerper, fj11d06 antikoerper, wu:fj11d06 antikoerper, zgc:73078 antikoerper, Cyclin-C antikoerper, CycC antikoerper, AI451004 antikoerper, AU020987 antikoerper, CG1C antikoerper, Cyclin C antikoerper, cyclin C antikoerper, cyclin C L homeolog antikoerper, cyclin-C antikoerper, CycC antikoerper, ccnc antikoerper, CCNC antikoerper, Ccnc antikoerper, ccnc.L antikoerper, LOC5577815 antikoerper

Hintergrund:

Synonyms: CycC, Cyclin-C, SRB11 homolog, hSRB11, CCNC

Background: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.

Gen-ID: 892

UniProt: P24863

Pathways: Zellzyklus, Regulation of Lipid Metabolism by PPARalpha