Laminin Antikörper (AA 901-1000)

Produktnummer ABIN728638

Produktdetails anti-Laminin Antikörper

Target: Laminin (LN)

Bindungsspezifität: AA 901-1000

Reaktivität: Human, Maus, Ratte, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Laminin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Kaninchen, Ratte

Homologie: Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Laminin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Laminin Antikörper (ABIN728638)

Miyauchi, Yasuchika, Fukumitsu, Ishii, Ogiso, Minami, Kojima, Yamaoka, Katayama, Kawai, Yoshitoshi-Uebayashi, Kita, Yasuda, Sasaki, Uemoto: "A novel three-dimensional culture system maintaining the physiological extracellular matrix of fibrotic model livers accelerates progression of hepatocellular carcinoma cells." in: Scientific reports, Vol. 7, Issue 1, pp. 9827, (2017) (PubMed).

Gong, Zhao, Liu, Lu, Liu, Zhou: "A Dynamically Tunable, Bioinspired Micropatterned Surface Regulates Vascular Endothelial and Smooth Muscle Cells Growth at Vascularization." in: Small (Weinheim an der Bergstrasse, Germany), Vol. 12, Issue 41, pp. 5769-5778, (2016) (PubMed).

Su, Zhang, Song, Shi, Fu, Xia, Bai, Hu, Xu, Song, Song: "Tetrachlorobenzoquinone activates nrf2 signaling by keap1 cross-linking and ubiquitin translocation but not keap1-cullin3 complex dissociation." in: Chemical research in toxicology, Vol. 28, Issue 4, pp. 765-74, (2015) (PubMed).

Details zu Laminin

Target: Laminin (LN)

Andere Bezeichnung: laminin (LN Produkte)

Synonyme: LAMC1 antikoerper, laminin antikoerper, laminin, beta 2 (laminin S) antikoerper, LAMB2 antikoerper

Hintergrund:

Synonyms: CLM, LIS5, Laminin subunit beta-1, Laminin B1 chain, Laminin-1 subunit beta, Laminin-10 subunit beta, Laminin-12 subunit beta, Laminin-2 subunit beta, Laminin-6 subunit beta, Laminin-8 subunit beta, LAMB1

Background: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.

Gen-ID: 3912

UniProt: P07942