Granulin Antikörper (AA 451-550)

Produktnummer ABIN728668

Produktdetails anti-Granulin Antikörper

Target: Granulin (GRN)

Bindungsspezifität: AA 451-550

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Granulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody is specific for Granulin-6

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Granulin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Granulin Antikörper (ABIN728668)

Thurner, Fadle, Regitz, Kemele, Klemm, Zaks, Stöger, Bette, Carbon, Zimmer, Assmann, Murawski, Kubuschok, Held, Preuss, Pfreundschuh: "The molecular basis for development of proinflammatory autoantibodies to progranulin." in: Journal of autoimmunity, Vol. 61, pp. 17-28, (2015) (PubMed).

Details zu Granulin

Target: Granulin (GRN)

Andere Bezeichnung: Granulin (GRN Produkte)

Synonyme: GRN antikoerper, grn antikoerper, wu:fb11g12 antikoerper, wu:fj18f05 antikoerper, MGC53354 antikoerper, DKFZp459H066 antikoerper, CLN11 antikoerper, GEP antikoerper, GP88 antikoerper, PCDGF antikoerper, PEPI antikoerper, PGRN antikoerper, epithelin antikoerper, acrogranin antikoerper, granulin precursor antikoerper, granulin a antikoerper, Granulins antikoerper, granulin L homeolog antikoerper, granulin antikoerper, GRN antikoerper, grna antikoerper, grn antikoerper, grn.L antikoerper, granulin antikoerper, ORF1 granulin antikoerper, Grn antikoerper

Substanzklasse: Viral Protein

Hintergrund:

Synonyms: GEP, GP88, PEPI, PGRN, CLN11, PCDGF, Granulins, Proepithelin, GRN

Background: Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.

Gen-ID: 2896

UniProt: P28799