BRMS1L Antikörper (AA 151-246)

Produktnummer ABIN730933

Produktdetails anti-BRMS1L Antikörper

Target: BRMS1L (Breast Cancer Metastasis-Suppressor 1-Like (BRMS1L))

Bindungsspezifität: AA 151-246

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRMS1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BRMS-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu BRMS1L

Target: BRMS1L (Breast Cancer Metastasis-Suppressor 1-Like (BRMS1L))

Andere Bezeichnung: BRMS-1 (BRMS1L Produkte)

Synonyme: BRMS1 antikoerper, 0710008O11Rik antikoerper, AI159718 antikoerper, D12Ertd407e antikoerper, MGC81249 antikoerper, brms1l antikoerper, im:7136473 antikoerper, zgc:114129 antikoerper, brms1 antikoerper, breast cancer metastasis-suppressor 1 like antikoerper, breast cancer metastasis-suppressor 1-like antikoerper, breast cancer metastasis-suppressor 1 like L homeolog antikoerper, breast cancer metastasis-suppressor 1-like a antikoerper, BRMS1L antikoerper, Brms1l antikoerper, brms1l.L antikoerper, brms1la antikoerper, brms1l antikoerper

Hintergrund:

Synonyms: Breast cancer metastasis-suppressor 1, BRMS1

Background: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.

Gen-ID: 25855

UniProt: Q9HCU9