SLC8A1 Antikörper (AA 801-900) (Cy5)
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- Target Alle SLC8A1 Antikörper anzeigen
- SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))
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Bindungsspezifität
- AA 801-900
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SLC8A1 Antikörper ist konjugiert mit Cy5
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Sheep,Pig,Horse,Chicken,Guinea Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NCX1
- Isotyp
- IgG
- Top Product
- Discover our top product SLC8A1 Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))
- Andere Bezeichnung
- NCX1/SLC8A1 (SLC8A1 Produkte)
- Synonyme
- NCX1 antikoerper, AI852629 antikoerper, AV344025 antikoerper, D930008O12Rik antikoerper, Ncx1 antikoerper, Ncx antikoerper, SLC8A1 antikoerper, ncx1n antikoerper, solute carrier family 8 member A1 antikoerper, solute carrier family 8 (sodium/calcium exchanger), member 1 antikoerper, solute carrier family 8 (sodium/calcium exchanger), member 1b antikoerper, sodium/calcium exchanger 1 antikoerper, SLC8A1 antikoerper, Slc8a1 antikoerper, slc8a1b antikoerper, Tsp_07038 antikoerper
- Hintergrund
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Synonyms: Na+/Ca2+exchanger 1, CNC, DKFZp779F0871, MGC119581 , FLJ37694, FLJ43417, Na+/Ca2+ exchange protein 1, Na+/Ca2+ exchanger, NCX 1, NCX, SLC8A1, SLC8A1 protein , Sodium Calcium Exchanger, Sodium/calcium exchanger 1, Solute carrier family 8 member 1.
Background: In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma(plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM].
- Gen-ID
- 6546
- Pathways
- Myometrial Relaxation and Contraction
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