MCAM Antikörper (AA 201-300)

Produktnummer ABIN732143

Produktdetails anti-MCAM Antikörper

Target: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Bindungsspezifität: AA 201-300

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCAM Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD146

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-MCAM Antikörper (ABIN732143)

Zhang, Chen, Liu, Zhou, Hu, Zhou, Han, Chen: "Exendin-4 promotes proliferation of adipose-derived stem cells through ERK and JNK signaling pathways." in: In vitro cellular & developmental biology. Animal, Vol. 52, Issue 5, pp. 598-606, (2016) (PubMed).

Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: "The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious." in: International journal of clinical and experimental pathology, Vol. 8, Issue 2, pp. 1525-34, (2015) (PubMed).

Details zu MCAM

Target: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Andere Bezeichnung: CD146/MCAM (MCAM Produkte)

Synonyme: CD146 antikoerper, MUC18 antikoerper, Muc18 antikoerper, 1-gicerin antikoerper, AV025631 antikoerper, CD149 antikoerper, s-endo antikoerper, s-gicerin antikoerper, cd146 antikoerper, gicerin antikoerper, id:ibd3512 antikoerper, mcam antikoerper, MCAM antikoerper, melanoma cell adhesion molecule antikoerper, melanoma cell adhesion molecule b antikoerper, MCAM antikoerper, Mcam antikoerper, mcamb antikoerper

Hintergrund:

Synonyms: CD146, MUC18, Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, MCAM

Background: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Gen-ID: 4162

UniProt: P43121