CXCR2 Antikörper (AA 316-360)

Produktnummer ABIN732218

Produktdetails anti-CXCR2 Antikörper

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Bindungsspezifität: AA 316-360

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CXCR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CXCR2 Antikörper (ABIN732218)

Li, Duan, Yu, Dang: "NFATc1 regulates cell proliferation, migration, and invasion of ovarian cancer SKOV3 cells in vitro and in vivo." in: Oncology reports, Vol. 36, Issue 2, pp. 918-28, (2017) (PubMed).

Alexeev, Donahue, Uitto, Igoucheva: "Chemotaxis-driven disease-site targeting of therapeutic adult stem cells in dystrophic epidermolysis bullosa." in: Stem cell research & therapy, Vol. 7, Issue 1, pp. 124, (2016) (PubMed).

Wang, Lu, Dey, Deng, Wu, Jiang, Fang, Zhao, Konaparthi, Hua, Zhang, Li-Ning-Tapia, Kapoor, Wu, Patel, Guo, Ramamoorthy, Tieu, Heffernan, Zhao, Shang, Khadka, Hou, Hu, Jin, Yao, Pan, Ding, Shi, Li et al.: "Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression. ..." in: Cancer discovery, Vol. 6, Issue 1, pp. 80-95, (2016) (PubMed).

Goetzenich, Kraemer, Rossaint, Bleilevens, Dollo, Siry, Rajabi-Alampour, Beckers, Soppert, Lue, Rex, Bernhagen, Stoppe: "The role of macrophage migration inhibitory factor in anesthetic-induced myocardial preconditioning." in: PLoS ONE, Vol. 9, Issue 3, pp. e92827, (2014) (PubMed).

Details zu CXCR2

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Andere Bezeichnung: CXCR2/CD182 (CXCR2 Produkte)

Hintergrund:

Synonyms: CD182, IL8R2, IL8RA, IL8RB, CMKAR2, CDw128b, C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8R B, IL-8 receptor type 2, CXCR2

Background: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

Gen-ID: 3579

UniProt: P25025

Pathways: cAMP Metabolic Process