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XBP1 Antikörper (AA 51-150) (Cy3)

XBP1 Reaktivität: Human, Maus WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy3
Produktnummer ABIN732731
  • Target Alle XBP1 Antikörper anzeigen
    XBP1 (X-Box Binding Protein 1 (XBP1))
    Bindungsspezifität
    • 17
    • 15
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 75
    • 41
    • 10
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    Human, Maus
    Wirt
    • 72
    • 13
    • 1
    Kaninchen
    Klonalität
    • 73
    • 13
    Polyklonal
    Konjugat
    • 44
    • 7
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser XBP1 Antikörper ist konjugiert mit Cy3
    Applikation
    • 72
    • 45
    • 27
    • 19
    • 13
    • 12
    • 12
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Spezifität
    XBP-1 antibody will recognize both isoforms, may also interact with chicken
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Cow,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human XBP-1
    Isotyp
    IgG
    Top Product
    Discover our top product XBP1 Primärantikörper
  • Applikationshinweise
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Li, Han, Shi: "IRE1?-XBP1 Pathway Is Activated Upon Induction of Single-Prolonged Stress in Rat Neurons of the Medial Prefrontal Cortex." in: Journal of molecular neuroscience : MN, (2015) (PubMed).

  • Target
    XBP1 (X-Box Binding Protein 1 (XBP1))
    Andere Bezeichnung
    Xbp1 (XBP1 Produkte)
    Synonyme
    treb5 antikoerper, xXBP1 antikoerper, xbp2 antikoerper, XBP1P1 antikoerper, XBPP1 antikoerper, xbp1 antikoerper, TREB5 antikoerper, XBP-1 antikoerper, XBP2 antikoerper, D11Ertd39e antikoerper, TREB-5 antikoerper, HTF antikoerper, cb918 antikoerper, id:ibd1195 antikoerper, trebf antikoerper, wu:fb02h05 antikoerper, wu:fb63f10 antikoerper, xbp1a antikoerper, xbp1b antikoerper, X-box binding protein 1 antikoerper, X-box binding protein 1 L homeolog antikoerper, xbp1 antikoerper, XBP1 antikoerper, Xbp1 antikoerper, xbp1.L antikoerper
    Hintergrund

    Synonyms: XBP2, TREB5, XBP-1, X-box-binding protein 1, Tax-responsive element-binding protein 5, XBP1

    Background: Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.

    Gen-ID
    7494
    UniProt
    P17861
    Pathways
    ER-Nucleus Signaling, Unfolded Protein Response
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