Glutamate Receptor 3 Antikörper (AA 451-550)

Produktnummer ABIN734603

Produktdetails anti-Glutamate Receptor 3 Antikörper

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Bindungsspezifität: AA 451-550

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 3 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GLUR3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Andere Bezeichnung: GLUR3/GRIA 3 (GRIA3 Produkte)

Synonyme: AMPA antikoerper, gria3 antikoerper, GRIN3A antikoerper, glur3b antikoerper, gria3.2 antikoerper, zfGRIA3[b] antikoerper, si:bz1o18.1 antikoerper, SI:zC231H1.1 antikoerper, si:zc140k5.3 antikoerper, GLUR3 antikoerper, GLUR-C antikoerper, GLUR3/C antikoerper, GRIA3 antikoerper, glur3 antikoerper, GluA3 antikoerper, GluR-3 antikoerper, GluR-C antikoerper, GluR-K3 antikoerper, GLUR-K3 antikoerper, GLURC antikoerper, MRX94 antikoerper, 2900064I19Rik antikoerper, Glur-3 antikoerper, Glur3 antikoerper, Gluralpha3 antikoerper, glutamate receptor, ionotropic, AMPA 3b antikoerper, glutamate ionotropic receptor AMPA type subunit 3 antikoerper, glutamate receptor, ionotropic, AMPA 3 antikoerper, glutamate receptor, ionotropic, AMPA 3 L homeolog antikoerper, glutamate receptor, ionotropic, AMPA3 (alpha 3) antikoerper, gria3b antikoerper, GRIA3 antikoerper, gria3 antikoerper, gria3.L antikoerper, Gria3 antikoerper

Hintergrund:

Synonyms: GLUR3, GLURC, GluA3, MRX94, GLUR-C, GLUR-K3, Glutamate receptor 3, GluR-3, AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, GRIA3

Background: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Gen-ID: 2892

UniProt: P42263

Pathways: PI3K-Akt Signalweg, cAMP Metabolic Process, Synaptic Membrane