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Haptoglobin Antikörper (AA 251-350)

HP Reaktivität: Human, Ratte, Maus WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN734738
  • Target Alle Haptoglobin (HP) Antikörper anzeigen
    Haptoglobin (HP)
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350
    Reaktivität
    • 101
    • 45
    • 40
    • 12
    • 9
    • 9
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 114
    • 19
    • 9
    • 7
    • 6
    • 2
    Kaninchen
    Klonalität
    • 133
    • 23
    Polyklonal
    Konjugat
    • 81
    • 26
    • 11
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Haptoglobin Antikörper ist unkonjugiert
    Applikation
    • 107
    • 59
    • 54
    • 23
    • 21
    • 21
    • 13
    • 13
    • 12
    • 12
    • 12
    • 11
    • 10
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This protein may interact with Peptidase S1 Domain in LPA.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Hpt
    Isotyp
    IgG
    Top Product
    Discover our top product HP Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Kälsch, Pott, Takeda, Kumamoto, Möllmann, Canbay, Sitek, Baba: "Bathing in carbon dioxide-enriched water alters protein expression in keratinocytes of skin tissue in rats." in: International journal of biometeorology, (2016) (PubMed).

  • Target
    Haptoglobin (HP)
    Abstract
    HP Produkte
    Synonyme
    HP antikoerper, wu:fb64e01 antikoerper, BP antikoerper, HP2ALPHA2 antikoerper, HPA1S antikoerper, HP-1 antikoerper, HPR antikoerper, Zonulin antikoerper, haptoglobin antikoerper, haptoglobin-like antikoerper, HP antikoerper, hp antikoerper, Hp antikoerper, LOC479668 antikoerper, LOC101102413 antikoerper
    Hintergrund

    Synonyms: BP, HPA1S, HP2ALPHA2, Haptoglobin, Zonulin, HP

    Background: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial, Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.

    Gen-ID
    3240
    UniProt
    P00738
    Pathways
    Transition Metal Ion Homeostasis
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