Midkine Antikörper

Produktnummer ABIN735338

Produktdetails anti-Midkine Antikörper

Target: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Midkine Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Midkine

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Midkine

Target: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Andere Bezeichnung: Midkine (MDK Produkte)

Synonyme: ARAP antikoerper, MK antikoerper, NEGF2 antikoerper, Mek antikoerper, MK-B antikoerper, PTF-alpha-1 antikoerper, mdk antikoerper, midkine antikoerper, negf2 antikoerper, RIHB antikoerper, cb518 antikoerper, fb79b05 antikoerper, fj33b02 antikoerper, fj48a12 antikoerper, mdk2 antikoerper, plei2 antikoerper, wu:fb79b05 antikoerper, wu:fj33b02 antikoerper, wu:fj48a12 antikoerper, MK-A antikoerper, PTF-alpha-2 antikoerper, X-PTF-alpha1 antikoerper, XMK antikoerper, mdk-a antikoerper, mdk-b antikoerper, midkine antikoerper, midkine L homeolog antikoerper, midkine (neurite growth-promoting factor 2) antikoerper, midkine b antikoerper, midkine S homeolog antikoerper, MDK antikoerper, Mdk antikoerper, mdk.L antikoerper, mdkb antikoerper, mdk.S antikoerper

Hintergrund:

Synonyms: MK, ARAP, NEGF2, Midkine, Amphiregulin-associated protein, Midgestation and kidney protein, Neurite outgrowth-promoting factor 2, Neurite outgrowth-promoting protein, MDK, MK1

Background: Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity).

Gen-ID: 4192

UniProt: P21741

Pathways: RTK Signalweg, M Phase, Skeletal Muscle Fiber Development