DUSP4 Antikörper (AA 301-394) (Biotin)
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- Target Alle DUSP4 Antikörper anzeigen
- DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
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Bindungsspezifität
- AA 301-394
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DUSP4 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus
- Homologie
- Rat,Dog,Cow,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MKP-2
- Isotyp
- IgG
- Top Product
- Discover our top product DUSP4 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
- Andere Bezeichnung
- MKP-2/DUSP4 (DUSP4 Produkte)
- Synonyme
- zgc:55423 antikoerper, DUSP4 antikoerper, typ antikoerper, hvh2 antikoerper, mkp2 antikoerper, mkp-2 antikoerper, MGC131045 antikoerper, HVH2 antikoerper, MKP-2 antikoerper, MKP2 antikoerper, TYP antikoerper, 2700078F24Rik antikoerper, AI844617 antikoerper, BB104621 antikoerper, E130306H24Rik antikoerper, Mkp-2 antikoerper, Mkp2 antikoerper, dual specificity phosphatase 4 antikoerper, dual specificity phosphatase 4 S homeolog antikoerper, dusp4 antikoerper, DUSP4 antikoerper, dusp4.S antikoerper, Dusp4 antikoerper
- Hintergrund
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Synonyms: Mitogen activated protein kinase phosphatase 2, Dual specicity phosphatase 4, Dual specicity protein phosphatase 4, Dual specicity protein phosphatase hVH2, DUSP 4, HVH 2, HVH2, MAP kinase phosphatase 2, Mitogen activated protein kinase phosphatase 2, MKP 2, MKP2, Serine/threonine specic protein phosphatase, TYP, VH 2, VH1 homologous phosphatase 2, VH2.
Background: DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
- Gen-ID
- 1846
- Pathways
- Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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