CD86 Antikörper (AA 140-175)

Produktnummer ABIN736701

Produktdetails anti-CD86 Antikörper

Target: CD86

Bindungsspezifität: AA 140-175

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD86 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Hund, Human, Maus, Ratte

Homologie: Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat CD86

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CD86 Antikörper (ABIN736701)

Lee, Yu, Trimpert, Benthani, Mairhofer, Richter-Pechanska, Wyler, Belenki, Kaltenbrunner, Pammer, Kausche, Firsching, Dietert, Schotsaert, Martínez-Romero, Singh, Kunz, Niemeyer, Ghanem, Salzer, Paar et al.: "Virus-induced senescence is a driver and therapeutic target in COVID-19. ..." in: Nature, Vol. 599, Issue 7884, pp. 283-289, (2021) (PubMed).

Han, Wang, Qin, Xia, Wu: "LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 83, (2018) (PubMed).

Chen, Zhang, Wang, Chen, Yan, Zhang, Zhang: "Peptide-modified chitosan hydrogels promote skin wound healing by enhancing wound angiogenesis and inhibiting inflammation." in: American journal of translational research, Vol. 9, Issue 5, pp. 2352-2362, (2017) (PubMed).

Zhang, Zhang, Yin, Li, Bao, Chen: "Variation and significance of secretory immunoglobulin A, interleukin 6 and dendritic cells in oral cancer." in: Oncology letters, Vol. 13, Issue 4, pp. 2297-2303, (2017) (PubMed).

Gerzanich, Makar, Guda, Kwon, Stokum, Woo, Ivanova, Ivanov, Mehta, Morris, Bryan, Bever, Simard: "Salutary effects of glibenclamide during the chronic phase of murine experimental autoimmune encephalomyelitis." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 177, (2017) (PubMed).

Xie, Wu, Zhou, Yang, Tian, Huang, Meng, Li: "PICK1 confers anti-inflammatory effects in acute liver injury via suppressing M1 macrophage polarization." in: Biochimie, Vol. 127, pp. 121-32, (2016) (PubMed).

Das, Singh, Majid, Sherman, Mukhopadhyay, Wright, Martin, Dunn, Baker: "Syndesome Therapeutics for Enhancing Diabetic Wound Healing." in: Advanced healthcare materials, Vol. 5, Issue 17, pp. 2248-60, (2016) (PubMed).

Chen, Li, Zhao, Liang, Ma, Li, Zhu: "Prevention of ultraviolet radiation‑induced immunosuppression by sunscreen in Candida albicans‑induced delayed‑type hypersensitivity." in: Molecular medicine reports, Vol. 14, Issue 1, pp. 202-8, (2016) (PubMed).

Ju, Xing, Yang, Zheng, Jia, Zhang, Ren: "An effective cytokine adjuvant vaccine induces autologous T-cell response against colon cancer in an animal model." in: BMC immunology, Vol. 17, Issue 1, pp. 31, (2016) (PubMed).

Chen, Shi, Zhang, Chen, Wang, Zhang, Tian, Yan, Li, Zhong, Xing, Zhang, Zhang: "Mesenchymal stem cell-laden anti-inflammatory hydrogel enhances diabetic wound healing." in: Scientific reports, Vol. 5, pp. 18104, (2016) (PubMed).

Evans, Jonason, Bussler, Torno, Veeraraghavan, Reilly, Doherty, Seils, Winter, Mallow, Kirk, Howell, Giralico, Scrivens, Klimatcheva, Fisher, Bowers, Paris, Smith, Zauderer: "Antibody blockade of semaphorin 4D promotes immune infiltration into tumor and enhances response to other immunomodulatory therapies." in: Cancer immunology research, (2015) (PubMed).

Gao, Zhang, Ding, Chen, Hu, Jiang, Li, Chen, Wang, Ye, Zhu: "Common expression of stemness molecular markers and early cardiac transcription factors in human Wharton's jelly-derived mesenchymal stem cells and embryonic stem cells." in: Cell transplantation, Vol. 22, Issue 10, pp. 1883-900, (2014) (PubMed).

Details zu CD86

Target: CD86

Andere Bezeichnung: CD86 (CD86 Produkte)

Synonyme: B7-2 antikoerper, B7.2 antikoerper, B70 antikoerper, CD28LG2 antikoerper, LAB72 antikoerper, B7 antikoerper, CLS1 antikoerper, Cd28l2 antikoerper, ETC-1 antikoerper, Ly-58 antikoerper, Ly58 antikoerper, MB7 antikoerper, MB7-2 antikoerper, TS/A-2 antikoerper, CD86 molecule antikoerper, CD86 antigen antikoerper, integrin subunit alpha 2b antikoerper, CD86 antikoerper, Cd86 antikoerper, Itga2b antikoerper

Hintergrund:

Synonyms: B7-2, Cd86 antigen, Cd86, Membrane glycoprotein

Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

Gen-ID: 56822

UniProt: O35531

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation