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KLF2/4 Antikörper (AA 415-513)

KLF2/4 Reaktivität: Human, Maus, Ratte WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p), ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN737121
  • Target Alle KLF2/4 Produkte
    KLF2/4 (Kruppel-Like Factor 2/4 (KLF2/4))
    Bindungsspezifität
    AA 415-513
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 15
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KLF2/4 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
    Spezifität
    This antibody may crossreact with KLF2 due to high sequence similarity.
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Cow,Sheep,Pig,Horse,Chicken,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KLF4
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Verma, Lovren, Pan, Yanagawa, Deb, Karkhanis, Quan, Teoh, Feder-Elituv, Moussa, Souza, Fremes: "Pedicled no-touch saphenous vein graft harvest limits vascular smooth muscle cell activation: the PATENT saphenous vein graft study." in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 45, Issue 4, pp. 717-25, (2014) (PubMed).

    El-Sayed, Zhang, Zhang, Liu, Abbott, Zhang, Li: "Pluripotent state induction in mouse embryonic fibroblast using mRNAs of reprogramming factors." in: International journal of molecular sciences, Vol. 15, Issue 12, pp. 21840-64, (2014) (PubMed).

    Lovren, Pan, Quan, Singh, Shukla, Gupta, Steer, Ingram, Gupta, Al-Omran, Teoh, Marsden, Verma: "MicroRNA-145 targeted therapy reduces atherosclerosis." in: Circulation, Vol. 126, Issue 11 Suppl 1, pp. S81-90, (2012) (PubMed).

  • Target
    KLF2/4 (Kruppel-Like Factor 2/4 (KLF2/4))
    Abstract
    KLF2/4 Produkte
    Hintergrund

    Synonyms: EZF, GKLF, Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4

    Background: Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

    Gen-ID
    9314
    UniProt
    O43474
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