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CHI3L1 Antikörper (AA 330-381)

CHI3L1 Reaktivität: Human, Maus, Ratte WB, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN737556
  • Target Alle CHI3L1 Antikörper anzeigen
    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
    Bindungsspezifität
    • 16
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 330-381
    Reaktivität
    • 47
    • 28
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 45
    • 5
    • 1
    Kaninchen
    Klonalität
    • 45
    • 5
    • 1
    Polyklonal
    Konjugat
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CHI3L1 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 15
    • 13
    • 13
    • 10
    • 8
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from rat CGP-39/CHI3L1
    Isotyp
    IgG
    Top Product
    Discover our top product CHI3L1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Ben, Qiu, Zhou, Zhou, Zhang, Wu, Ju, Ni: "Ovalbumin enhances YKL-40, IL-5, GM-CSF, and eotaxin expression simultaneously in primarily cultured mouse tracheal epithelial cells." in: In vitro cellular & developmental biology. Animal, Vol. 50, Issue 3, pp. 243-50, (2014) (PubMed).

    Tanaka, Matsumoto, Inoue, Umeda, Takai, Sumida: "Antigen-specific over-expression of human cartilage glycoprotein 39 on CD4+ CD25+ forkhead box protein 3+ regulatory T cells in the generation of glucose-6-phosphate isomerase-induced arthritis." in: Clinical and experimental immunology, Vol. 177, Issue 2, pp. 419-27, (2014) (PubMed).

  • Target
    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
    Andere Bezeichnung
    CHI3L1 (CHI3L1 Produkte)
    Synonyme
    AW208766 antikoerper, Brp39 antikoerper, Gp39 antikoerper, ASRT7 antikoerper, CGP-39 antikoerper, GP-39 antikoerper, GP39 antikoerper, HC-gp39 antikoerper, HCGP-3P antikoerper, YKL-40 antikoerper, YKL40 antikoerper, YYL-40 antikoerper, hCGP-39 antikoerper, GP38K antikoerper, CLP-1 antikoerper, SPC-40 antikoerper, SPS-40 antikoerper, Chil1 antikoerper, BP40 antikoerper, MGP-40 antikoerper, chitinase-like 1 antikoerper, chitinase 3 like 1 antikoerper, chitinase 3-like 1 (cartilage glycoprotein-39) antikoerper, Chil1 antikoerper, CHI3L1 antikoerper, Chi3l1 antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund

    Synonyms: Chitinase-3-like protein 1, Cartilage glycoprotein 39, CGP-39, GP-39, Chi3l1

    Background: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung (By similarity).

    Molekulargewicht
    42kDa
    Gen-ID
    89824
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