IQGAP1 Antikörper (AA 1451-1550)

Produktnummer ABIN737796

Produktdetails anti-IQGAP1 Antikörper

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Bindungsspezifität: AA 1451-1550

Reaktivität: Human, Ratte, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IQGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Kaninchen, Ratte

Homologie: Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IQGAP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-IQGAP1 Antikörper (ABIN737796)

Fang, Zhang, Liu, Li, Zhou, Song, Zhao, Feng, Zhang, Li, Wen: "PAX6 downregulates miR-124 expression to promote cell migration during embryonic stem cell differentiation." in: Stem cells and development, Vol. 23, Issue 19, pp. 2297-310, (2014) (PubMed).

Details zu IQGAP1

Target: IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

Andere Bezeichnung: IQGAP1 (IQGAP1 Produkte)

Synonyme: HUMORFA01 antikoerper, SAR1 antikoerper, p195 antikoerper, AA682088 antikoerper, D7Ertd237e antikoerper, D7Ertd257e antikoerper, mKIAA0051 antikoerper, IQ motif containing GTPase activating protein 1 antikoerper, IQGAP1 antikoerper, Iqgap1 antikoerper

Hintergrund:

Synonyms: SAR1, p195, HUMORFA1, Ras GTPase-activating-like protein IQGAP1, IQGAP1, KIAA51

Background: Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.

Gen-ID: 8826

UniProt: P46940

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2