Serotonin Receptor 1A Antikörper (AA 301-400)

Produktnummer ABIN738006

Produktdetails anti-Serotonin Receptor 1A Antikörper

Target: Serotonin Receptor 1A (HTR1A)

Bindungsspezifität: AA 301-400

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat 5-HTR1A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Serotonin Receptor 1A Antikörper (ABIN738006)

García-Pedraza, Fernández-González, López, Martín, Alarcón-Torrecillas, Rodríguez-Barbero, Morán, García-Domingo: "Oral fluoxetine treatment changes serotonergic sympatho-regulation in experimental type 1 diabetes." in: Life sciences, Vol. 293, pp. 120335, (2022) (PubMed).

Yeh, Weng, Chang, Chan, Huang, Chu, Wei, Ma, Cheng, Ma, Chen, Shyu: "Calcitonin alleviates hyperalgesia in osteoporotic rats by modulating serotonin transporter activity." in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, Vol. 27, Issue 11, pp. 3355-3364, (2016) (PubMed).

Zhou, Wu, Zhou, Liu, Lee, Liu, Devkota, Ro, Zhu, Suh: "Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert(-/-) mice." in: Translational psychiatry, Vol. 6, Issue 6, pp. e836, (2016) (PubMed).

Details zu Serotonin Receptor 1A

Target: Serotonin Receptor 1A (HTR1A)

Andere Bezeichnung: 5-HTR1A (HTR1A Produkte)

Synonyme: 5-HT-dro2A antikoerper, 5-HT1ADro antikoerper, 5-HT[1A]Dro antikoerper, 5-HT[[1ADro]] antikoerper, 5-HT[[1A]] antikoerper, 5-HT[[1A]]DRO antikoerper, 5HT-R2A antikoerper, 5HT-dro2A antikoerper, 5HT-drp[[2A]] antikoerper, 5HT1A antikoerper, 5HT[[1ADro]] antikoerper, 5htdro2a antikoerper, CG16720 antikoerper, DRO2A antikoerper, Dm5HTdro2A antikoerper, Dmel\\CG16720 antikoerper, d5-HT1A antikoerper, 5htr1a antikoerper, htr1a antikoerper, HTR1A antikoerper, Htr1a antikoerper, 5-Ht1a antikoerper, Gpcr18 antikoerper, 5-HT-1A antikoerper, 5-HT1A antikoerper, 5HT1a antikoerper, ADRB2RL1 antikoerper, ADRBRL1 antikoerper, G-21 antikoerper, PFMCD antikoerper, RAT5HT1A antikoerper, 5ht1a antikoerper, adrb2rl1 antikoerper, adrbrl1 antikoerper, htr1a-A antikoerper, 5-hydroxytryptamine (serotonin) receptor 1A antikoerper, 5-hydroxytryptamine receptor 1A antikoerper, 5-hydroxytryptamine (serotonin) receptor 1A a antikoerper, 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog antikoerper, 5-HT1A antikoerper, HTR1A antikoerper, htr1aa antikoerper, Htr1a antikoerper, htr1a.L antikoerper

Hintergrund:

Synonyms: 5HT1A, RAT5HT1A, 5-hydroxytryptamine receptor 1A, 5-HT-1A, 5-HT1A, Serotonin receptor 1A, Htr1a

Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

Gen-ID: 24473

UniProt: P19327

Pathways: JAK-STAT Signalweg, Synaptic Membrane, Feeding Behaviour