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GM1123 Antikörper (AA 21-120) (Biotin)

GM1123 Reaktivität: Human, Maus, Ratte WB, IHC (fro), IHC (p), ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN739577
  • Target Alle GM1123 Produkte
    GM1123 (Predicted Gene 1123 (GM1123))
    Bindungsspezifität
    AA 21-120
    Reaktivität
    • 18
    • 18
    • 18
    • 3
    • 3
    • 3
    Human, Maus, Ratte
    Wirt
    • 18
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GM1123 Antikörper ist konjugiert mit Biotin
    Applikation
    • 18
    • 17
    • 13
    • 13
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Coxsackie Adenovirus Receptor
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    GM1123 (Predicted Gene 1123 (GM1123))
    Andere Bezeichnung
    Coxsackie Adenovirus Receptor (GM1123 Produkte)
    Synonyme
    AV052824 antikoerper, CLSP antikoerper, predicted gene 1123 antikoerper, coxsackie virus and adenovirus receptor-like 1-like antikoerper, Gm1123 antikoerper, LOC100359797 antikoerper
    Hintergrund

    Synonyms: CAR, HCAR, CAR4/6, Coxsackievirus and adenovirus receptor, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR, CXADR

    Background: Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

    Gen-ID
    1525
    UniProt
    P78310
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