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IL4 Receptor Antikörper (AA 201-300)

IL4R Reaktivität: Human, Maus WB, ELISA, FACS, ICC, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN740565
  • Target Alle IL4 Receptor (IL4R) Antikörper anzeigen
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    Bindungsspezifität
    • 16
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reaktivität
    • 65
    • 49
    • 22
    Human, Maus
    Wirt
    • 76
    • 12
    • 8
    • 2
    • 1
    Kaninchen
    Klonalität
    • 81
    • 17
    • 1
    Polyklonal
    Konjugat
    • 50
    • 9
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL4 Receptor Antikörper ist unkonjugiert
    Applikation
    • 79
    • 31
    • 27
    • 14
    • 13
    • 13
    • 11
    • 9
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IL4R
    Isotyp
    IgG
    Top Product
    Discover our top product IL4R Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Danelli, Frossi, Gri, Mion, Guarnotta, Bongiovanni, Tripodo, Mariuzzi, Marzinotto, Rigoni, Blank, Colombo, Pucillo: "Mast cells boost myeloid-derived suppressor cell activity and contribute to the development of tumor-favoring microenvironment." in: Cancer immunology research, Vol. 3, Issue 1, pp. 85-95, (2015) (PubMed).

  • Target
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    Andere Bezeichnung
    IL4R (IL4R Produkte)
    Synonyme
    IL4R antikoerper, il-4ra antikoerper, zgc:113063 antikoerper, CD124 antikoerper, IL-4RA antikoerper, IL4RA antikoerper, Il4ra antikoerper, IL4 antikoerper, Il4r antikoerper, interleukin 4 receptor antikoerper, interleukin 4 receptor, tandem duplicate 1 antikoerper, interleukin 4 receptor, alpha antikoerper, IL4R antikoerper, il4r.1 antikoerper, Il4r antikoerper, Il4ra antikoerper
    Hintergrund

    Synonyms: CD124, IL4RA, IL-4RA, Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL4R, 582J2.1

    Background: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.

    Gen-ID
    3566
    UniProt
    P24394
    Pathways
    JAK-STAT Signalweg, Positive Regulation of Immune Effector Process
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