AIMP2 Antikörper (AA 201-300) (Biotin)

Produktnummer ABIN741302

Produktdetails anti-AIMP2 Antikörper (Biotin)

Target: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Bindungsspezifität: AA 201-300

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIMP2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AIMP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu AIMP2

Target: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Andere Bezeichnung: AIMP2 (AIMP2 Produkte)

Synonyme: jtv1 antikoerper, MGC53242 antikoerper, pro0992 antikoerper, JTV1 antikoerper, JTV-1 antikoerper, P38 antikoerper, AA407136 antikoerper, AA407225 antikoerper, Aimp2(p38) antikoerper, Jtv1 antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 antikoerper, aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antikoerper, aimp2.L antikoerper, aimp2 antikoerper, AIMP2 antikoerper, Aimp2 antikoerper

Hintergrund:

Synonyms: P38, JTV1, JTV-1, PRO0992, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Multisynthase complex auxiliary component p38, Protein JTV-1, AIMP2

Background: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Gen-ID: 7965

UniProt: Q13155