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SLAMF7 Antikörper (AA 51-160)

SLAMF7 Reaktivität: Human, Maus WB, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN741825
  • Target Alle SLAMF7 Antikörper anzeigen
    SLAMF7 (SLAM Family Member 7 (SLAMF7))
    Bindungsspezifität
    • 15
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 51-160
    Reaktivität
    • 48
    • 21
    • 2
    Human, Maus
    Wirt
    • 34
    • 15
    • 3
    Kaninchen
    Klonalität
    • 37
    • 15
    Polyklonal
    Konjugat
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SLAMF7 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 21
    • 16
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Cow
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SLAMF7
    Isotyp
    IgG
    Top Product
    Discover our top product SLAMF7 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    SLAMF7 (SLAM Family Member 7 (SLAMF7))
    Andere Bezeichnung
    SLAMF7/CD319/CS1 (SLAMF7 Produkte)
    Hintergrund

    Synonyms: 19A, 19A24 protein, CD 319, CD2 like receptor activating cytotoxic cells, CD2 subset 1, CD319, CD319 antigen, CRACC, CS1, Membrane protein FOAP 12, Novel Ly9, Novel LY9 lymphocyte antigen 9 like protein, Protein 19A, SLAM family member 7, SLAMF 7.

    Background: SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.

    UniProt
    Q9NQ25
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