ICOS Antikörper (AA 51-150)
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- Target Alle ICOS Antikörper anzeigen
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
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Bindungsspezifität
- AA 51-150
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ICOS Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- This antibody may also have a secondary cross-reactivity with AP-1 complex-associated regulatory protein due to a 77 % non-contiguous sequence similarity in the corresponding immunogen region.
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ICOS
- Isotyp
- IgG
- Top Product
- Discover our top product ICOS Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Andere Bezeichnung
- ICOS/CD278 (ICOS Produkte)
- Synonyme
- ICOS antikoerper, AILIM antikoerper, CCLP antikoerper, CRP-1 antikoerper, H4 antikoerper, Ly115 antikoerper, CD278 antikoerper, CVID1 antikoerper, Ailim antikoerper, inducible T-cell costimulator antikoerper, inducible T cell co-stimulator antikoerper, inducible T-cell co-stimulator antikoerper, ICOS antikoerper, LOC100232284 antikoerper, Icos antikoerper
- Hintergrund
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Synonyms: AILIM, CD278, CVID1, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, ICOS
Background: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
- Gen-ID
- 29851
- UniProt
- Q9Y6W8
- Pathways
- Cancer Immune Checkpoints
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