MAP2K6 Antikörper (pSer202)

Produktnummer ABIN743903

Produktdetails anti-MAP2K6 Antikörper

Target: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Bindungsspezifität: pSer202

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP2K6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MEK6 around the phosphorylation site of Ser202

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu MAP2K6

Target: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Andere Bezeichnung: MEK6 (MAP2K6 Produkte)

Synonyme: MAPKK6 antikoerper, MEK6 antikoerper, MKK6 antikoerper, PRKMK6 antikoerper, SAPKK-3 antikoerper, SAPKK3 antikoerper, Mkk6 antikoerper, Prkmk6 antikoerper, MKK3 antikoerper, map2k3 antikoerper, zMKK3 antikoerper, map2k6 antikoerper, mitogen-activated protein kinase kinase 6 antikoerper, mitogen-activated protein kinase kinase 6 L homeolog antikoerper, MAP2K6 antikoerper, Map2k6 antikoerper, map2k6 antikoerper, map2k6.L antikoerper

Hintergrund:

Synonyms: MAP kinase kinase 6, MAPK/ERK kinase 6, MAPKK6, MEK6, Mitogen Activated Protein Kinase Kinase 6, MKK 6, MKK6, PRKMK6, SAPKK3, Dual specicity mitogen activated protein kinase kinase 6, MKK 6, Dual specicity mitogen activated protein kinase kinase 6, EC 2.7.12.2, MP2K6_HUMAN.

Background: Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Gen-ID: 5608

Pathways: MAPK Signalweg, TLR Signalweg, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades