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MAP3K11 Antikörper (pSer281, pThr277)

MAP3K11 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN743963
  • Target Alle MAP3K11 Antikörper anzeigen
    MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
    Bindungsspezifität
    • 15
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer281, pThr277
    Reaktivität
    • 52
    • 33
    • 27
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 47
    • 4
    Kaninchen
    Klonalität
    • 49
    • 3
    Polyklonal
    Konjugat
    • 22
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAP3K11 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 22
    • 13
    • 13
    • 6
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Pig,Rabbit,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human MLK3 around the phosphorylation site of Thr277/Ser281
    Isotyp
    IgG
    Top Product
    Discover our top product MAP3K11 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
    Andere Bezeichnung
    MLK3 + (MAP3K11 Produkte)
    Synonyme
    MEKK11 antikoerper, MLK-3 antikoerper, MLK3 antikoerper, PTK1 antikoerper, SPRK antikoerper, 2610017K16Rik antikoerper, Mlk3 antikoerper, Mlk-3 antikoerper, RHOE antikoerper, mitogen-activated protein kinase kinase kinase 11 antikoerper, MAP3K11 antikoerper, Map3k11 antikoerper
    Hintergrund

    Synonyms: MLK3, PTK1, SPRK, MLK-3, MEKK11, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11

    Background: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

    Gen-ID
    4296
    UniProt
    Q16584
    Pathways
    MAPK Signalweg, Interferon-gamma Pathway
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