CDC42 Antikörper (pSer71)

Produktnummer ABIN745298

Produktdetails anti-CDC42 Antikörper

Target: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Bindungsspezifität: pSer71

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC42 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human CDC42 around the phosphorylation site of Ser71

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CDC42

Target: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Andere Bezeichnung: CDC42 (CDC42 Produkte)

Synonyme: CDC42Hs antikoerper, G25K antikoerper, AI747189 antikoerper, AU018915 antikoerper, cdc42a antikoerper, wu:fb07d08 antikoerper, wu:fj62g06 antikoerper, zgc:63918 antikoerper, Xcdc42 antikoerper, cdc42hs antikoerper, g25k antikoerper, CDC42 antikoerper, CG12530 antikoerper, Cdc42Dm antikoerper, D-CDC42 antikoerper, D-Cdc42 antikoerper, D-cdc42 antikoerper, DCDC42 antikoerper, DCdc42 antikoerper, Dcdc42 antikoerper, Dm Cdc42 antikoerper, DmCDC42 antikoerper, Dmcdc42 antikoerper, Dmel\\CG12530 antikoerper, cdc42 antikoerper, cell division cycle 42 antikoerper, Cell division control protein 42 homolog antikoerper, cell division control protein 42 homolog antikoerper, cell division cycle 42 L homeolog antikoerper, CG12530 gene product from transcript CG12530-RC antikoerper, Rho family GTPase antikoerper, CDC42 antikoerper, Cdc42 antikoerper, cdc42 antikoerper, LOC100636735 antikoerper, LOC100637699 antikoerper, LOC100638834 antikoerper, cdc42.L antikoerper

Hintergrund:

Synonyms: CDC 42, CDC42Hs, Cell division control protein 42 homolog, Cell division cycle 42, Cell division cycle 42 isoform 1, Cell division cycle 42 isoform 2, dJ224A6.1.1, dJ224A6.1.2, G25K, G25K GTP binding protein, Growth regulating protein, GTP binding protein 25kD, Small GTP binding protein CDC42.

Background: The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013].

Gen-ID: 998

Pathways: MAPK Signalweg, Microtubule Dynamics, RTK Signalweg, WNT Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling