Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

INPP5D Antikörper (pTyr1020)

INPP5D Reaktivität: Human, Maus, Affe WB, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN745733
  • Target Alle INPP5D Antikörper anzeigen
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    Bindungsspezifität
    • 18
    • 17
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1020
    Reaktivität
    • 89
    • 65
    • 42
    • 19
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Affe
    Wirt
    • 85
    • 5
    Kaninchen
    Klonalität
    • 75
    • 15
    Polyklonal
    Konjugat
    • 31
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser INPP5D Antikörper ist unkonjugiert
    Applikation
    • 57
    • 20
    • 17
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Kreuzreaktivität
    Human, Affe, Maus
    Homologie
    Rat,Dog,Cow,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human SHIP1 around the phosphorylation site of Tyr1020
    Isotyp
    IgG
    Top Product
    Discover our top product INPP5D Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    Andere Bezeichnung
    SHIP1 (INPP5D Produkte)
    Synonyme
    INPP5D antikoerper, 256.t00004 antikoerper, 13.t00027 antikoerper, ship antikoerper, ship1 antikoerper, AI323613 antikoerper, SHIP antikoerper, SHIP-1 antikoerper, SHIP1 antikoerper, s-SHIP antikoerper, SIP-145 antikoerper, hp51CN antikoerper, inositol polyphosphate-5-phosphatase D antikoerper, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 antikoerper, inositol polyphosphate 5-phosphatase antikoerper, inositol polyphosphate-5-phosphatase D L homeolog antikoerper, INPP5D antikoerper, LOC100446045 antikoerper, inpp5d antikoerper, EHI_159880 antikoerper, EHI_153490 antikoerper, inpp5d.L antikoerper, LOC100380693 antikoerper, Inpp5d antikoerper
    Hintergrund

    Synonyms: P-SHIP1 Tyr1020, Inositol polyphosphate 5 phosphatase of 145 kDa, 4, 5-trisphosphate 5-phosphatase 1, hp51CN, hSHIP, Inositol polyphosphate 5 phosphatase 145 kDa, Inositol polyphosphate 5 phosphatase, Inositol polyphosphate 5 phosphatase D, Inositol polyphosphate-5-phosphatase of 145 kDa, INPP 5D, INPP5D, INPP5D protein, MGC104855, MGC142140, MGC142142, p150 ship, p150Ship, Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 1, Phosphatidylinositol-3, SH2 containing inositol 5 phosphatase, SH2 containing inositol phosphatase isoform b, SH2 domain containing inositol 5' phosphatase 1, SH2 domain containing inositol phosphatase 1, SH2 domain-containing inositol phosphatase 1, SH2 domain-containing inositol-5''-phosphatase 1, SHIP 1, SHIP-1, SHIP1, SHIP1_RAT, Signaling inositol polyphosphate 5 phosphatase SIP 145, Signaling inositol polyphosphate 5 phosphatase SIP145, SIP 145, SIP-145, SIP145.

    Background: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.

    Gen-ID
    3635
    Pathways
    T-Zell Rezeptor Signalweg, BCR Signaling, Warburg Effekt
Sie sind hier:
Kundenservice