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CRTC2 Antikörper (pSer171) (Biotin)

CRTC2 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN745990
  • Target Alle CRTC2 Antikörper anzeigen
    CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer171
    Reaktivität
    • 72
    • 21
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 64
    • 6
    • 4
    • 1
    Kaninchen
    Klonalität
    • 68
    • 7
    Polyklonal
    Konjugat
    • 30
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CRTC2 Antikörper ist konjugiert mit Biotin
    Applikation
    • 61
    • 42
    • 19
    • 17
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171
    Isotyp
    IgG
    Top Product
    Discover our top product CRTC2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
    Andere Bezeichnung
    TORC2 (CRTC2 Produkte)
    Synonyme
    CRTC2 antikoerper, TORC-2 antikoerper, TORC2 antikoerper, 4632407F12Rik antikoerper, Torc2 antikoerper, mTORC2 antikoerper, RGD1308903 antikoerper, CREB regulated transcription coactivator 2 antikoerper, CRTC2 antikoerper, Crtc2 antikoerper
    Hintergrund

    Synonyms: TORC2, TORC-2, CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, Transducer of CREB protein 2, CRTC2

    Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

    Gen-ID
    200186
    UniProt
    Q53ET0
    Pathways
    AMPK Signaling, Carbohydrate Homeostasis
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