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tau Antikörper (pSer396)

Name: tau Antikörper (pSer396)
SKU: ABIN746453
Price: 384.62 EUR
Availability: InStock

Reaktivität: Human, Maus, Ratte WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat brain labeled with Anti-phospho-Tau protein(Ser396) Polyclonal Antibody, Unconjugated (ABIN746453) at 1:200 followed by conjugation to the secondary antibody (tau Antikörper (pSer396))

IHC

Formalin-fixed and paraffin embedded mouse brain labeled with Anti-phospho-Tau protein(Ser396) Polyclonal Antibody, Unconjugated (ABIN746453) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C and DAPI staining (tau Antikörper (pSer396))

Formalin-fixed and paraffin embedded Human endometrium labeled with Anti-phospho-Tau protein(Ser396) Polyclonal Antibody, Unconjugated (ABIN746453) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C and DAPI staining (tau Antikörper (pSer396))

3 Abbildungen

(1 reference)

Produktnummer ABIN746453

Datenblatt (PDF)

Target Alle tau Antikörper anzeigen

tau (tau Protein)
Bindungsspezifität
31

30

30

30

27

27

25

25

24

24

24

23

23

22

17

17

17

16

16

16

16

16

15

15

13

12

11

10

9

8

7

7

6

5

5

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2
pSer396
Reaktivität
579

541

538

42

28

27

18

7

3

2

2

1

1
Human, Maus, Ratte
Wirt
684

38

3

2
Kaninchen
Passende Sekundärantikörper
Klonalität
661

65

1
Polyklonal
Konjugat
238

40

31

29

24

24

24

24

24

24

24

24

24

22

22

15

15

15

15

15

15

12

5

4

4

4

4

4

1

1
Dieser tau Antikörper ist unkonjugiert
Applikation
570

271

262

213

92

85

68

58

54

37

34

17

12

12

12

9

2

2

1

1
Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human, Maus, Ratte

Homologie

Dog

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser396 [KT(p-S)T]

Isotyp

IgG

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Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Cai, Yan, Wang: "Minocycline alleviates beta-amyloid protein and tau pathology via restraining neuroinflammation induced by diabetic metabolic disorder." in: Clinical interventions in aging, Vol. 8, pp. 1089-95, (2013) (PubMed).
Target

tau (tau Protein)

Abstract

tau Produkte

Synonyme

DDPAC antikoerper, FTDP-17 antikoerper, MAPTL antikoerper, MSTD antikoerper, MTBT1 antikoerper, MTBT2 antikoerper, PPND antikoerper, TAU antikoerper, tau antikoerper, PHF-tau antikoerper, microtubule associated protein tau antikoerper, MAPT antikoerper

Hintergrund

Synonyms: TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, PPP1R13, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT
Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Gen-ID

4137

UniProt

P10636