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IL12RB2 Antikörper (AA 301-400)

IL12RB2 Reaktivität: Human WB, ELISA, IF (p), IHC (fro), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN747878
  • Target Alle IL12RB2 Antikörper anzeigen
    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
    Bindungsspezifität
    • 14
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    Reaktivität
    • 50
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 10
    • 1
    Kaninchen
    Klonalität
    • 48
    • 8
    Polyklonal
    Konjugat
    • 27
    • 7
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL12RB2 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 22
    • 19
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IL-12RB2
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Filková, Vernerová, Hulejová, Prajzlerová, Veigl, Pavelka, Vencovský, Šenolt: "Pro-inflammatory effects of interleukin-35 in rheumatoid arthritis." in: Cytokine, Vol. 73, Issue 1, pp. 36-43, (2015) (PubMed).

  • Target
    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
    Andere Bezeichnung
    IL12RB2 (IL12RB2 Produkte)
    Synonyme
    IL12RB2 antikoerper, A930027I18Rik antikoerper, IL-12RB2 antikoerper, Ifnm antikoerper, interleukin 12 receptor subunit beta 2 antikoerper, interleukin 12 receptor, beta 2 antikoerper, IL12RB2 antikoerper, Il12rb2 antikoerper
    Hintergrund

    Synonyms: Interleukin-12 receptor subunit beta-2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2, IL12RB2

    Background: Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.

    Gen-ID
    3595
    UniProt
    Q99665
    Pathways
    JAK-STAT Signalweg
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