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LAG3 Antikörper (AA 210-260) (PE)

Name: LAG3 Antikörper (AA 210-260) (PE)
SKU: ABIN748518
Price: 479.69 EUR
Availability: InStock

LAG3 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal PE

(1 reference)

Produktnummer ABIN748518

Datenblatt (PDF)

Target Alle LAG3 Antikörper anzeigen

LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
Bindungsspezifität
15

14

9

7

7

4

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 210-260
Reaktivität
86

37

8

4

3

2

1

1

1
Human, Maus, Ratte
Wirt
51

34

12

4
Kaninchen
Passende Sekundärantikörper
Klonalität
52

46

1
Polyklonal
Konjugat
53

7

6

4

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser LAG3 Antikörper ist konjugiert mit PE
Applikation
67

36

33

29

24

21

15

13

13

10

9

6

5

2

2

1

1

1

1

1

1
Western Blotting (WB)

Kreuzreaktivität

Human, Maus

Homologie

Rat,Cow,Pig,Horse,Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3

Isotyp

IgG

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LAG3 Reaktivität: Human, Maus WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB21775 unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 66-199) antibody
LAG3 Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 4H6A3 unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibody
LAG3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibody
LAG3 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 8B12E10 unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (N-Term) antibody
LAG3 Reaktivität: Human WB, ELISA, IHC, FACS, ICC, IP Wirt: Maus Monoclonal L4-PL33 unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 1-360) antibody
LAG3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 244-487) antibody
LAG3 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 209-451) antibody
LAG3 Reaktivität: Ratte WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibody
LAG3 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 201-300) antibody
LAG3 Reaktivität: Human, Maus WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

FCM(1:20-100)

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit

12 months
Parodi, Battaglia, Kalli, Ferrera, Conteduca, Tardito, Stringara, Ivaldi, Negrini, Borgonovo, Simonato, Traverso, Carmignani, Fenoglio, Filaci: "CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes." in: Cancer immunology, immunotherapy : CII, Vol. 62, Issue 5, pp. 851-62, (2013) (PubMed).
Target

LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Andere Bezeichnung

Lymphocyte Activation Gene 3 (LAG3 Produkte)

Synonyme

CD223 antikoerper, LAG-3 antikoerper, Ly66 antikoerper, lymphocyte activating 3 antikoerper, lymphocyte-activation gene 3 antikoerper, LAG3 antikoerper, Lag3 antikoerper

Hintergrund

Synonyms: CD223, Lymphocyte activation gene 3 protein, LAG-3, Lag3
Background: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.

Gen-ID

297596

UniProt

Q5BK54

Pathways

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints