Leukotriene B4 Receptor/BLT Antikörper (AA 101-200)

Produktnummer ABIN748628

Produktdetails anti-Leukotriene B4 Receptor/BLT Antikörper

Target: Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

Bindungsspezifität: AA 101-200

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Leukotriene B4 Receptor/BLT Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LTB4-R1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Leukotriene B4 Receptor/BLT Antikörper (ABIN748628)

Zinn, Sisignano, Kern, Pierre, Tunaru, Jordan, Suo, Treutlein, Angioni, Ferreiros, Leffler, DeBruin, Offermanns, Geisslinger, Scholich: "The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons." in: The Journal of biological chemistry, Vol. 292, Issue 15, pp. 6123-6134, (2017) (PubMed).

Details zu Leukotriene B4 Receptor/BLT

Target: Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

Andere Bezeichnung: LTB4-R1/BLTR (LTB4R Produkte)

Synonyme: BLT1 antikoerper, BLTR antikoerper, CMKRL1 antikoerper, GPR16 antikoerper, LTB4R1 antikoerper, LTBR1 antikoerper, P2RY7 antikoerper, P2Y7 antikoerper, Ltb4r1 antikoerper, LTB4R antikoerper, lt4r1 antikoerper, Ltb4r antikoerper, mBLTR antikoerper, leukotriene B4 receptor antikoerper, leukotriene B4 receptor-like antikoerper, Leukotriene B4 receptor 1 antikoerper, leukotriene B4 receptor 1 antikoerper, LTB4R antikoerper, Ltb4r antikoerper, LOC415617 antikoerper, lt4r1 antikoerper, Ltb4r1 antikoerper

Hintergrund:

Synonyms: BLT1, BLTR, P2Y7, GPR16, LTBR1, P2RY7, CMKRL1, LTB4R1, Leukotriene B4 receptor 1, LTB4-R 1, LTB4-R1, Chemoattractant receptor-like 1, G-protein coupled receptor 16, P2Y purinoceptor 7, LTB4R, BLT

Background: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.

Gen-ID: 1241

UniProt: Q15722