TREM2 Antikörper (AA 1-100)

Produktnummer ABIN749678

Produktdetails anti-TREM2 Antikörper

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Bindungsspezifität: AA 1-100

Reaktivität: Maus, Human, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TREM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Maus, Schwein, Ratte

Homologie: Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TREM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-TREM2 Antikörper (ABIN749678)

Abdi, Pasbakhsh, Shabani, Nekoonam, Sadeghi, Fathi, Abouzaripour, Mohamed, Zibara, Kashani, Zendedel: "Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis." in: Neurotoxicity research, (2021) (PubMed).

Rai, Dietz, Dilisio, Radwan, Agrawal: "Vitamin D attenuates inflammation, fatty infiltration, and cartilage loss in the knee of hyperlipidemic microswine." in: Arthritis research & therapy, Vol. 18, Issue 1, pp. 203, (2016) (PubMed).

Satoh, Kawana, Yamamoto, Ishida, Saito, Arima: "A survey of TREM2 antibodies reveals neuronal but not microglial staining in formalin-fixed paraffin-embedded postmortem Alzheimer's brain tissues." in: Alzheimer's research & therapy, Vol. 5, Issue 4, pp. 30, (2014) (PubMed).

Details zu TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Andere Bezeichnung: TREM2 (TREM2 Produkte)

Synonyme: TREM-A1 antikoerper, TREM-B1 antikoerper, TREM2 antikoerper, trem-2 antikoerper, trem2a antikoerper, trem2b antikoerper, trem2c antikoerper, TREM-2 antikoerper, Trem2a antikoerper, Trem2b antikoerper, Trem2c antikoerper, triggering receptor expressed on myeloid cells 2 antikoerper, trem-like transcript 2 protein antikoerper, TREM2 antikoerper, trem2 antikoerper, LOC100228399 antikoerper, Trem2 antikoerper

Hintergrund:

Synonyms: TREM-2, Trem2a, Trem2b, Trem2c, Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, TREM2

Background: May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.

Gen-ID: 54209

UniProt: Q9NZC2