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Glucagon Receptor Antikörper (AA 11-110)

Name: Glucagon Receptor Antikörper (AA 11-110)
SKU: ABIN751528
Price: 384.62 EUR
Availability: InStock

GCGR Reaktivität: Human, Ratte, Maus WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Mouse kidney lysates probed with Glucagon Receptor Polyclonal Antibody, unconjugated at 1:300 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C. (Glucagon Receptor Antikörper (AA 11-110))

Formalin-fixed and paraffin embedded rat heart labeled with Anti Glucagon Receptor Polyclonal Antibody, Unconjugated (ABIN751528) followed by conjugation to the secondary antibody and DAB staining (Glucagon Receptor Antikörper (AA 11-110))

IHC

Paraformaldehyde-fixed, paraffin embedded rat brain tissue, Antigen retrieval by boiling in sodium citrate buffer (pH6. (Glucagon Receptor Antikörper (AA 11-110))

IHC (p)

Paraformaldehyde-fixed, paraffin embedded human stomach tissue, Antigen retrieval by boiling in sodium citrate buffer (pH6. (Glucagon Receptor Antikörper (AA 11-110))

IHC (p)

4 Abbildungen

(1 reference)

Produktnummer ABIN751528

Datenblatt (PDF)

Target Alle Glucagon Receptor (GCGR) Antikörper anzeigen

Glucagon Receptor (GCGR)
Bindungsspezifität
15

6

3

3

2

1

1

1

1

1

1

1
AA 11-110
Reaktivität
49

29

28

4

4

3

3

3

3

1

1
Human, Ratte, Maus
Wirt
47

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
48

1
Polyklonal
Konjugat
16

4

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Glucagon Receptor Antikörper ist unkonjugiert
Applikation
31

16

16

12

12

8

7

7

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human, Maus, Ratte

Homologie

Dog,Cow,Pig,Chicken,Guinea Pig

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human Glucagon Receptor

Isotyp

IgG
anti-Glucagon Receptor (GCGR) (AA 26-136) antibody
GCGR Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Glucagon Receptor (GCGR) (AA 1-140) antibody
GCGR Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Glucagon Receptor (GCGR) (N-Term) antibody
GCGR Reaktivität: Human, Rind (Kuh), Affe, Hund, Hamster, Pferd IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Glucagon Receptor (GCGR) (Internal Region) antibody
GCGR Reaktivität: Human, Ratte, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Glucagon Receptor (GCGR) antibody
GCGR Reaktivität: Human IF, BR Wirt: Maus Monoclonal hGR-2 F6 unconjugated Recombinant Antibody

anti-Glucagon Receptor (GCGR) (N-Term) antibody
GCGR Reaktivität: Human, Affe IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Glucagon Receptor (GCGR) (Extracellular Domain) antibody
GCGR Reaktivität: Human, Affe IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Glucagon Receptor (GCGR) (Internal Region) antibody
Recent GCGR Reaktivität: Human ELISA Wirt: Ziege Polyclonal unconjugated

anti-Glucagon Receptor (GCGR) (1st Extracellular Loop), (AA 200-212) antibody
GCGR Reaktivität: Human, Ratte, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Glucagon Receptor (GCGR) (Internal Region) antibody
GCGR Reaktivität: Human, Ratte, Maus WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Rafacho, Gonçalves-Neto, Santos-Silva, Alonso-Magdalena, Merino, Taboga, Carneiro, Boschero, Nadal, Quesada: "Pancreatic alpha-cell dysfunction contributes to the disruption of glucose homeostasis and compensatory insulin hypersecretion in glucocorticoid-treated rats." in: PLoS ONE, Vol. 9, Issue 4, pp. e93531, (2014) (PubMed).
Target

Glucagon Receptor (GCGR)

Andere Bezeichnung

Glucagon Receptor (GCGR Produkte)

Synonyme

GCGR antikoerper, GGR antikoerper, GR antikoerper, glucagon receptor antikoerper, GCGR antikoerper, Gcgr antikoerper

Hintergrund

Synonyms: GGR, GL-R, Glucagon receptor, GCGR
Background: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.

Gen-ID

2642

UniProt

P47871

Pathways

Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process