PRKAG3 Antikörper (AA 151-250)
-
- Target Alle PRKAG3 Antikörper anzeigen
- PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
-
Bindungsspezifität
- AA 151-250
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser PRKAG3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human AMPK gamma 3
- Isotyp
- IgG
- Top Product
- Discover our top product PRKAG3 Primärantikörper
-
-
- Applikationshinweise
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
- Andere Bezeichnung
- Ampk gamma 3/Prkag3 (PRKAG3 Produkte)
- Synonyme
- Ampkg3 antikoerper, prkag3-a antikoerper, PRKAG3 antikoerper, AMPKG3 antikoerper, AMPKg3L antikoerper, AMPKg3S antikoerper, Amkg3 antikoerper, protein kinase AMP-activated non-catalytic subunit gamma 3 antikoerper, protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog antikoerper, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b antikoerper, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit antikoerper, Prkag3 antikoerper, PRKAG3 antikoerper, prkag3.S antikoerper, prkag3-b antikoerper
- Hintergrund
-
Synonyms: AMPKG3, 5'-AMP-activated protein kinase subunit gamma-3, AMPK gamma3, AMPK subunit gamma-3, PRKAG3
Background: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
- Gen-ID
- 53632
- UniProt
- Q9UGI9
- Pathways
- AMPK Signaling, Cellular Glucan Metabolic Process, Warburg Effekt
-