Glycogen Synthase 2 Antikörper (AA 621-703)

Produktnummer ABIN752173

Produktdetails anti-Glycogen Synthase 2 Antikörper

Target: Glycogen Synthase 2 (GYS2) (Glycogen Synthase 2, Liver (GYS2))

Bindungsspezifität: AA 621-703

Reaktivität: Maus, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glycogen Synthase 2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Maus, Schwein

Homologie: Human,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glycogen synthase 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Glycogen Synthase 2 Antikörper (ABIN752173)

Scheffler, Park, Roach, Gerrard: "Gain of function AMP-activated protein kinase γ3 mutation (AMPKγ3R200Q) in pig muscle increases glycogen storage regardless of AMPK activation." in: Physiological reports, Vol. 4, Issue 11, (2016) (PubMed).

Details zu Glycogen Synthase 2

Target: Glycogen Synthase 2 (GYS2) (Glycogen Synthase 2, Liver (GYS2))

Andere Bezeichnung: Glycogen synthase 2 (GYS2 Produkte)

Synonyme: cb765 antikoerper, zgc:112057 antikoerper, BC021322 antikoerper, LGS antikoerper, GLYSN antikoerper, glycogen synthase 2 antikoerper, gys2 antikoerper, Gys2 antikoerper, GYS2 antikoerper

Hintergrund:

Synonyms: Glycogen starch synthase liver, Glycogen starch synthase liver, EC 2.4.1.11, Glycogen synthase 2 liver, GYS2, GYS2_HUMAN.

Background: Glycogen synthase catalyzes the rate-limiting step in glycogen synthesis. Its activity is regulated by a complex phosphorylation-dephosphorylation mechanism and by allosteric stimulators and inhibitors. Two isozymes of synthase, a skeletal muscle type (Glycogen synthase 1 - GYS1) and a liver type (Glycogen synthase 2 - GYS2), have been identified.

Gen-ID: 2998

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process