ATG12 Antikörper (AA 101-187)

Produktnummer ABIN752518

Produktdetails anti-ATG12 Antikörper

Target: ATG12 (Autophagy Related 12 (ATG12))

Bindungsspezifität: AA 101-187

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATG12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-ATG12 Antikörper (ABIN752518)

Song, Kou, Zou, Gao, Zeng, Xie: "Involvement of autophagy in tri-ortho-cresyl phosphate- induced delayed neuropathy in hens." in: Neurochemistry international, Vol. 64, pp. 1-8, (2013) (PubMed).

Details zu ATG12

Target: ATG12 (Autophagy Related 12 (ATG12))

Andere Bezeichnung: Apg12 (ATG12 Produkte)

Synonyme: APG12 antikoerper, APG12L antikoerper, FBR93 antikoerper, HAPG12 antikoerper, Apg12l antikoerper, AUTOPHAGY 12 antikoerper, AUTOPHAGY 12 B antikoerper, CG10861 antikoerper, Dmel\\CG10861 antikoerper, atg12 antikoerper, ATG12 antikoerper, apg12 antikoerper, DDBDRAFT_0185323 antikoerper, DDBDRAFT_0191412 antikoerper, DDB_0185323 antikoerper, DDB_0191412 antikoerper, 4931423H11Rik antikoerper, A330058M13Rik antikoerper, Atg12l antikoerper, AO090001000593 antikoerper, autophagy related 12 antikoerper, Ubiquitin-like superfamily protein antikoerper, Atg12p antikoerper, autophagy protein antikoerper, ubiquitin-like protein ATG12B antikoerper, autophagy associated protein Atg12 antikoerper, Autophagy-related 12 antikoerper, ATG12 autophagy related 12 homolog (S. cerevisiae) antikoerper, ATG12 autophagy related 12 homolog (S. cerevisiae) pseudogene antikoerper, autophagy associated ubiquitin-like modifier Atg12 antikoerper, hypothetical protein antikoerper, Autophagy-related protein 12 (Autophagy-related ubiquitin-like modifier ATG12) antikoerper, autophagy protein 12 antikoerper, autophagy related 12 S homeolog antikoerper, autophagy-related protein 12 antikoerper, ATG12 antikoerper, Atg12 antikoerper, APG12B antikoerper, APG12 antikoerper, LOC9321066 antikoerper, apg12 antikoerper, atg12 antikoerper, LOC743425 antikoerper, CAALFM_C113950CA antikoerper, atg12.S antikoerper, ANI_1_922094 antikoerper, AOR_1_1064164 antikoerper

Hintergrund:

Synonyms: APG12, FBR93, APG12L, HAPG12, Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like, ATG12

Background: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG1 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.

Gen-ID: 9140

UniProt: O94817

Pathways: Autophagie