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ATG12 Antikörper (AA 101-187)

ATG12 Reaktivität: Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN752518
  • Target Alle ATG12 Antikörper anzeigen
    ATG12 (Autophagy Related 12 (ATG12))
    Bindungsspezifität
    • 18
    • 14
    • 8
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-187
    Reaktivität
    • 85
    • 36
    • 26
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Maus, Ratte
    Wirt
    • 77
    • 23
    • 2
    • 1
    Kaninchen
    Klonalität
    • 79
    • 24
    Polyklonal
    Konjugat
    • 46
    • 9
    • 8
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATG12 Antikörper ist unkonjugiert
    Applikation
    • 81
    • 48
    • 37
    • 32
    • 21
    • 12
    • 12
    • 9
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ATG12
    Isotyp
    IgG
    Top Product
    Discover our top product ATG12 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Song, Kou, Zou, Gao, Zeng, Xie: "Involvement of autophagy in tri-ortho-cresyl phosphate- induced delayed neuropathy in hens." in: Neurochemistry international, Vol. 64, pp. 1-8, (2013) (PubMed).

  • Target
    ATG12 (Autophagy Related 12 (ATG12))
    Andere Bezeichnung
    Apg12 (ATG12 Produkte)
    Synonyme
    APG12 antikoerper, APG12L antikoerper, FBR93 antikoerper, HAPG12 antikoerper, Apg12l antikoerper, AUTOPHAGY 12 antikoerper, AUTOPHAGY 12 B antikoerper, CG10861 antikoerper, Dmel\\CG10861 antikoerper, atg12 antikoerper, ATG12 antikoerper, apg12 antikoerper, DDBDRAFT_0185323 antikoerper, DDBDRAFT_0191412 antikoerper, DDB_0185323 antikoerper, DDB_0191412 antikoerper, 4931423H11Rik antikoerper, A330058M13Rik antikoerper, Atg12l antikoerper, AO090001000593 antikoerper, autophagy related 12 antikoerper, Ubiquitin-like superfamily protein antikoerper, Atg12p antikoerper, autophagy protein antikoerper, ubiquitin-like protein ATG12B antikoerper, autophagy associated protein Atg12 antikoerper, Autophagy-related 12 antikoerper, ATG12 autophagy related 12 homolog (S. cerevisiae) antikoerper, ATG12 autophagy related 12 homolog (S. cerevisiae) pseudogene antikoerper, autophagy associated ubiquitin-like modifier Atg12 antikoerper, hypothetical protein antikoerper, Autophagy-related protein 12 (Autophagy-related ubiquitin-like modifier ATG12) antikoerper, autophagy protein 12 antikoerper, autophagy related 12 S homeolog antikoerper, autophagy-related protein 12 antikoerper, ATG12 antikoerper, Atg12 antikoerper, APG12B antikoerper, APG12 antikoerper, LOC9321066 antikoerper, apg12 antikoerper, atg12 antikoerper, LOC743425 antikoerper, CAALFM_C113950CA antikoerper, atg12.S antikoerper, ANI_1_922094 antikoerper, AOR_1_1064164 antikoerper
    Hintergrund

    Synonyms: APG12, FBR93, APG12L, HAPG12, Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like, ATG12

    Background: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG1 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.

    Gen-ID
    9140
    UniProt
    O94817
    Pathways
    Autophagie
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