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G6PC Antikörper (Cy5)

G6PC Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein WB, IF (p) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN753002
  • Target Alle G6PC Antikörper anzeigen
    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
    Reaktivität
    • 42
    • 21
    • 20
    • 15
    • 13
    • 12
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Schwein
    Wirt
    • 42
    • 1
    Kaninchen
    Klonalität
    • 42
    • 1
    Polyklonal
    Konjugat
    • 12
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser G6PC Antikörper ist konjugiert mit Cy5
    Applikation
    • 30
    • 19
    • 15
    • 11
    • 10
    • 4
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Rind (Kuh), Hund, Human, Maus, Schwein, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase alpha
    Isotyp
    IgG
    Top Product
    Discover our top product G6PC Primärantikörper
  • Applikationshinweise
    IF(IHC-P)(1:100-500)
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
    Andere Bezeichnung
    Glucose 6 phosphatase alpha (G6PC Produkte)
    Synonyme
    AW107337 antikoerper, G6Pase antikoerper, G6pt antikoerper, Glc-6-Pase antikoerper, G6PC1 antikoerper, G6PT antikoerper, GSD1 antikoerper, GSD1a antikoerper, G-6-Pase antikoerper, glucose-6-phosphatase, catalytic antikoerper, glucose-6-phosphatase catalytic subunit antikoerper, glucose-6-phosphatase, catalytic subunit antikoerper, G6pc antikoerper, G6PC antikoerper
    Hintergrund

    Synonyms: glucose-6-phosphatase, catalytic subunit, GSD1, AW107337, G-6-Pase, G6Pase, G6Pase-alpha, g6pc, G6PC_HUMAN, G6PT, Glucose-6-phosphatase alpha, Glucose-6-phosphatase, GSD1a, MGC163350, MGC93613, RP23-281C18.19.

    Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-i±, a second form, designated G6Pase-i², contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-i², also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-i² hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-i² may play an integral role in diabetes and glycogen storage diseases (GSDs).

    Molekulargewicht
    40kDa
    Gen-ID
    2538
    Pathways
    Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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