BRIP1 Antikörper (Biotin)

Produktnummer ABIN753720

Dieses Anti-BRIP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BRIP1 in WB und IHC (p). Geeignet für Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Pferd und Schwein.

Kurzübersicht für BRIP1 Antikörper (Biotin) (ABIN753720)

Target: BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))

Reaktivität: Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRIP1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BRIP1 Antikörper (Biotin)

Kreuzreaktivität: Maus, Ratte (Rattus), Kaninchen, Rind (Kuh), Schwein, Pferd, Hund, Huhn

Aufreinigung: Antibodies are purified by protein A and peptide affinity chromatography.

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human BACH1
Please inquire for sequence information.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1mg/1ml

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu BRIP1

Target: BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))

Andere Bezeichnung: BACH1/BRIP1

Hintergrund: BACH1 is a member of the DEAH helicase family that interacts with BRCA1 in vivo. BACH1 is a DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. BACH1 acts late in the Fanconi anemia pathway after FANCD2 ubiquitination and is involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. The BACH1/BRCA1 complex formation contributes to a key function of BRCA1. Therefore it is likely that BACH1 is a target of germline cancer-inducing mutations.
Synonym: BACH 1, BRIP1, BACH-1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1, BRCA1 binding helicase like protein BACH1, BRCA1 interacting protein C terminal helicase 1, BRIP 1, BRIP-1, FANCJ, ATP dependent RNA helicase BRIP1, Fanconi anemia group J protein, FLJ90232, MGC126521, MGC126523, OF antibody Protein FACJ.

Molekulargewicht: 130kDa

Gen-ID: 571

Pathways: DNA Reparatur