PLCL1 Antikörper (AA 1001-1096)

Produktnummer ABIN754588

Produktdetails anti-PLCL1 Antikörper

Target: PLCL1 (phospholipase C-Like 1 (PLCL1))

Bindungsspezifität: AA 1001-1096

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLCL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody may exhibit a slight secondary cross-reactivity with PLCL2 due to a 69 % non-sequential sequence similarity over the immunogen range.

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PLCL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PLCL1

Target: PLCL1 (phospholipase C-Like 1 (PLCL1))

Andere Bezeichnung: PLCL1 (PLCL1 Produkte)

Synonyme: PLCE antikoerper, PLCL antikoerper, PLDL1 antikoerper, PRIP antikoerper, C230017K02Rik antikoerper, PLC-L antikoerper, PLC-L1 antikoerper, PRIP-1 antikoerper, phospholipase C like 1 (inactive) antikoerper, phospholipase C-like 1 antikoerper, PLCL1 antikoerper, Plcl1 antikoerper

Hintergrund:

Synonyms: PLCL1, PLCE, Phospholipase C deleted in lung carcinoma, Phospholipase C epsilon, Phospholipase C like 1, Phospholipase C related but catalytically inactive protein, Phospholipase C related, but catalytically inactive protein, PLCE, PLCL, PRIP, Plcl1, C230017K02Rik, KIAA1092, PLC-L, PLC-L1, PLCE, PLCL, PRIP, PRIP-1, PLCL1_HUMAN.

Background: PLCL1 is involved an inositol phospholipid based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and sphatidylinositol. Component in the dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.

Gen-ID: 5334