Angiomotin Antikörper (AA 545-620)

Produktnummer ABIN754873

Produktdetails anti-Angiomotin Antikörper

Target: Angiomotin (AMOT)

Bindungsspezifität: AA 545-620

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiomotin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Angiomotin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Angiomotin Antikörper (ABIN754873)

Shimada, Abe, Kohno, Satohisa, Konno, Takahashi, Hatakeyama, Arimoto, Kakuki, Kaneko, Takano, Saito, Kojima: "Loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in human endometrial cancer." in: Scientific reports, Vol. 7, pp. 37049, (2017) (PubMed).

Details zu Angiomotin

Target: Angiomotin (AMOT)

Andere Bezeichnung: Angiomotin (AMOT Produkte)

Synonyme: C81439 antikoerper, CAG-2 antikoerper, D0Kist1 antikoerper, E230009N18Rik antikoerper, Sii6 antikoerper, mKIAA1071 antikoerper, RGD1564027 antikoerper, si:dkey-13f9.6 antikoerper, wu:fj21a07 antikoerper, angiomotin antikoerper, microRNA 4329 antikoerper, AMOT antikoerper, Amot antikoerper, MIR4329 antikoerper, amot antikoerper

Hintergrund:

Synonyms: Angiomotin, AMOT, KIAA171

Background: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.

Gen-ID: 154796

UniProt: Q4VCS5

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size