CDC6 Antikörper (pSer54)

Produktnummer ABIN756997

Produktdetails anti-CDC6 Antikörper

Target: CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

Bindungsspezifität: pSer54

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Cdc6 around the phosphorylation site of Ser54 [PL(p-S)PR]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CDC6

Target: CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

Andere Bezeichnung: Cdc6 (CDC6 Produkte)

Synonyme: CDC18L antikoerper, HsCDC18 antikoerper, HsCDC6 antikoerper, cell division cycle 6 antikoerper, CDC6 antikoerper, Cdc6 antikoerper

Hintergrund:

Synonyms: Cell Division Cycle protein 6, Cdc 18L, Cdc 6, CDC18 cell division cycle 18, S.pombe, homolog like, CDC18 S.pombe, CDC18 like, CDC18S.pombe, Cdc18L, CDC6 related protein, Cdc6p, Cell cycle controller, Cell division control protein 6, Cell division control protein 6 homolog, Cell division cycle 18, Cell division cycle 18 homolog, Cell division cycle 6 homolog, Cell division cycle 6 protein, HsCDC 18, HsCDC 6, HsCDC18, HsCDC6, p62, p62cdc 6, p62cdc6, CDC6_HUMAN.

Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Gen-ID: 990

Pathways: DNA Replication, Synthesis of DNA