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DAXX Antikörper (pSer517)

DAXX Reaktivität: Human, Ratte, Maus WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN757687
  • Target Alle DAXX Antikörper anzeigen
    DAXX (Death-Domain Associated Protein (DAXX))
    Bindungsspezifität
    • 23
    • 21
    • 16
    • 15
    • 15
    • 15
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer517
    Reaktivität
    • 174
    • 61
    • 48
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 157
    • 18
    Kaninchen
    Klonalität
    • 148
    • 27
    Polyklonal
    Konjugat
    • 63
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Dieser DAXX Antikörper ist unkonjugiert
    Applikation
    • 147
    • 77
    • 77
    • 42
    • 34
    • 26
    • 21
    • 18
    • 18
    • 12
    • 7
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human DAXX around the phosphorylation site of Ser517
    Isotyp
    IgG
    Top Product
    Discover our top product DAXX Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    DAXX (Death-Domain Associated Protein (DAXX))
    Andere Bezeichnung
    DAXX (DAXX Produkte)
    Synonyme
    BING2 antikoerper, DAP6 antikoerper, EAP1 antikoerper, LOC100226911 antikoerper, daxx antikoerper, si:dz179b20.7 antikoerper, wu:fd15c03 antikoerper, death domain associated protein antikoerper, Fas death domain-associated protein antikoerper, 28S ribosomal protein S29, mitochondrial antikoerper, death-domain associated protein antikoerper, death-associated protein 6 L homeolog antikoerper, DAXX antikoerper, Daxx antikoerper, LOC100226911 antikoerper, daxx.L antikoerper, daxx antikoerper
    Hintergrund

    Synonyms: BING 2, BING2, DAP 6, DAP6, Death associated protein 6, Death domain associated protein 6, EAP 1, EAP1, ETS1 associated protein 1, Fas death domain associated protein, hDaxx, MGC126245, MGC126246, DAXX_HUMAN.

    Background: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED3 protease family. A novel DD containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx is a death domain containing important intermediate in the Fas mediated apoptosis. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N terminal kinase (JNK) pathway. It is widely expressed in fetal and adult human and mouse tissue, indicating its important function in Fas signaling pathways.

    Gen-ID
    1616
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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